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COVID-19 | Corona Virus: Epidemiology, Pathophysiology, Diagnostics

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COVID-19 | Coronavirus: Epidemiology, Pathophysiology, Diagnostics

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Ninja Nerds,
What is Corona virus? What is COVID-19? Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). Coronavirus disease (COVID-19) caused by SARS-COV2 is a new strain that was discovered in 2019 and has not been previously identified in humans.
Coronaviruses are zoonotic, meaning they are transmitted between animals and people.  Detailed investigations found that SARS-CoV was transmitted from civet cats to humans and MERS-CoV from camels to humans. Several known coronaviruses are circulating in animals that have not yet infected humans. It is believed that COVID-19 was transmitted from pangolin to humans (current theory).
Common signs of infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death (WHO, 2020).
Ninja Nerd Lectures has compiled the most up to date and recent data on COVID-19 as of March 15, 2020. Please follow along with this lecture to understand the origin and zoonosis of COVID-19, the routes of transmission, epidemiology (current as of 3/15/2020), pathophysiology, and diagnostic tests used to identify COVID-19.
As new information and research is published we will continue to provide updates on COVID-19 and ensure all of our viewers are kept up to date on the most recent data.

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REFERENCES: World Health Organization (WHO), Centers for Disease Control and Prevention (CDC).


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COVID-19 | Coronavirus: Epidemiology, Pathophysiology | APRIL UPDATE

Ninja Nerds,
Join us for our lecture on COVID-19 where Ninja Nerd Science will go into detail on the virology, epidemiology, and pathophysiology/pathology of COVID-19. This is our April update on our previous lecture to keep all of our viewers informed on the new research and publications that have been released on COVID-19. Please be aware— This lecture is up to date as of April 17, 2020.

Coronaviruses are a large family of viruses which may cause illness in animals or humans.  In humans, several coronaviruses are known to cause respiratory infections ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). The most recently discovered coronavirus causes coronavirus disease COVID-19.

COVID-19 is the infectious disease caused by the most recently discovered coronavirus. This new virus and disease were unknown before the outbreak began in Wuhan, China, in December 2019.

The most common symptoms of COVID-19 are fever, tiredness, and dry cough. Some patients may have aches and pains, nasal congestion, runny nose, sore throat or diarrhea. These symptoms are usually mild and begin gradually. Some people become infected but don’t develop any symptoms and don't feel unwell. Most people (about 80%) recover from the disease without needing special treatment. Around 1 out of every 6 people who gets COVID-19 becomes seriously ill and develops difficulty breathing. Older people, and those with underlying medical problems like high blood pressure, heart problems or diabetes, are more likely to develop serious illness. People with fever, cough and difficulty breathing should seek medical attention.

World Health Organization (WHO) | 8 April 2020

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COVID-19 | Coronavirus: How is Coronavirus Diagnosed | APRIL UPDATE

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Ninja Nerds,

Join us for our lecture on COVID-19 where Ninja Nerd Science will go into detail on the diagnostics used to diagnose COVID-19. This is our April update on our previous lecture to keep all of our viewers informed on the new research and publications that have been released on COVID-19. Please be aware— This lecture is up to date as of April 17, 2020.

Coronaviruses are a large family of viruses which may cause illness in animals or humans.  In humans, several coronaviruses are known to cause respiratory infections ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). The most recently discovered coronavirus causes coronavirus disease COVID-19.

COVID-19 is the infectious disease caused by the most recently discovered coronavirus. This new virus and disease were unknown before the outbreak began in Wuhan, China, in December 2019.

The most common symptoms of COVID-19 are fever, tiredness, and dry cough. Some patients may have aches and pains, nasal congestion, runny nose, sore throat or diarrhea. These symptoms are usually mild and begin gradually. Some people become infected but don’t develop any symptoms and don't feel unwell. Most people (about 80%) recover from the disease without needing special treatment. Around 1 out of every 6 people who gets COVID-19 becomes seriously ill and develops difficulty breathing. Older people, and those with underlying medical problems like high blood pressure, heart problems or diabetes, are more likely to develop serious illness. People with fever, cough and difficulty breathing should seek medical attention.

World Health Organization (WHO) | 8 April 2020
Adventitious Lung sounds: Referenced from easyauscultation.com

REFERENCES | We have a thorough list of our references in AMA format found on our Facebook & Instagram social media sites

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COVID-19 (SARS Coronavirus 2) - timeline, pathophysiology (ARDS), coronavirus life cycle, treatment

The World health organization (WHO) has declared COVID-19 a pandemic. COVID 19 stands for coronavirus disease 2019 and is caused by the severe acute respiratory syndrome coronavirus 2.

Coronaviruses are a large family of viruses that are common in people and many different species of animals including cats and bats. Common human coronavirus typically causes a URTI, like the common cold. Most people get infected with one or more of these viruses at some point in their lives. The human coronavirus infection typically resolves on its own with basic rest while feeling miserable.

Rarely, the coronaviruses that infect animals can evolve and become a new human coronavirus which then infect and spread between people. Important examples of these type of coronavirus include severe acute respiratory syndrome coronavirus, SARS CoV for short in 2003 and Middle East respiratory syndrome coronavirus also known as MERS.
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COVID 19 Part 1: Basic Pathophysiology

Part one in a series as of 17 March 2020.

COVID-19 | Pathophysiology

How does the coronavirus (SARS-CoV-2) that causes the disease COVID-19 attack the body?
In this video, Dr Mike explains how the virus gets into the cells of the body and produces cough, pneumonia, cytokine storm, and acute respiratory distress syndrome (ARDS).

Instagram: @drmiketodorovic

Severe Acute Respiratory Syndrome (SARS) and COVID-19 – Coronaviruses | Lecturio

This video “Coronaviruses (2019-nCoV Wuhan update)” is part of the Lecturio course “Microbiology” ► WATCH the complete course on

► LEARN ABOUT:
– Characteristics of Coronaviradae
– Diseases caused by Coronaviradae, including SARS and the 2019 nCoV outbreak

FREE RESOURCES FOR STUDENTS AND EDUCATORS:
► The COVID-19 Concept Card, which covers the etiology, transmission, epidemiology, clinical presentation, diagnostics, management, and prevention of COVID-19 in one easy-to-digest place:
► The full COVID-19 Video Course, which covers the overview and management of the virus:
► The Studying at Home Guide, which includes some of our best tips for staying focused, being productive, and organizing your study space:
► The Teaching and Learning Continuity Package, with information for institutions to ensure the continuity of teaching through the COVID-19 pandemic:

► THE PROF: Dr. Sean Elliott earned his MD from Columbia University College of Physicians and Surgeons in 1993, followed by a Pediatric Residency at Children’s Memorial Hospital, Northwestern University School of Medicine, and a fellowship in Pediatric Infectious Diseases at St. Louis Children’s Hospital, Washington University School of Medicine. Recruited in 1999 at the University of Arizona College of Medicine, he is now the Professor of Pediatrics and the Associate Chair for the Department of Pediatrics, serving as the Pediatrics Residency Program Director from 2011 to the end of 2017 and as the interim Associate Dean of Curriculum from 2017 through 2019.

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COVID-19 (Coronavirus Disease 19) August Update- causes, symptoms, diagnosis, treatment, pathology

Watch the Osmosis Video here:

What is COVID-19 (Coronavirus Disease 19)? The coronaviruses that circulate among humans are typically benign, and they cause about a quarter of all common cold illnesses. But occasionally, coronaviruses, like COVID-19, circulate in an animal reservoir and mutate just enough to where they’re able to start infecting and causing disease in humans.

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Our Mission: To empower the world’s clinicians and caregivers with the best learning experience possible. Learn more here:

Medical disclaimer: Knowledge Diffusion Inc (DBA Osmosis) does not provide medical advice. Osmosis and the content available on Osmosis's properties (Osmosis.org, YouTube, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.

Covid-19 Disease -Pathophysiology and Clinical features

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).The disease was first identified in 2019 in Wuhan, the capital of China's Hubeiprovince, and has since spread globally, resulting in the 2019–2020 coronavirus pandemic. Common symptoms include fever, cough, and shortness of breath. Other symptoms may include muscle pain, sputumproduction, diarrhea, sore throat, abdominal pain, and loss of smell or taste.While the majority of cases result in mild symptoms, some progress to pneumonia and multi-organ failure. As of March 25, 2020, the overall rate of deaths per number of diagnosed casesis 4.5 percent; ranging from 0.2 percent to 15 percent according to age group and other health problems.

Coronavirus COVID-19 | Viral Structure & Pathogenesis

Welcome to this video on the COVID-19 disease caused by the SARS-CoV-2 coronavirus. In this tutorial we will discuss:

- Structure of the SARS-CoV-2 virus and its structural glycoproteins
- ACE-2 receptor interaction and mechanisms of host cell entry
- Pathogenesis and mechanism of ARDS
- Typical chest radiograph and CT appearances

We hope you have found this video informative - see references below for further reading.

Peter & Jack

References used in the making of this video:

1. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020 Feb 15;395(10223):497–506.
2. Schoeman D, Fielding BC. Coronavirus envelope protein: current knowledge. Virol J. 2019 May 27;16(1):69.
3. Weiss SR, Navas-Martin S. Coronavirus Pathogenesis and the Emerging Pathogen Severe Acute Respiratory Syndrome Coronavirus. Microbiol Mol Biol Rev. 2005 Dec;69(4):635–64.
4. Lin L, Lu L, Cao W, Li T. Hypothesis for potential pathogenesis of SARS-CoV-2 infection–a review of immune changes in patients with viral pneumonia. Emerg Microbes Infect. 2020 Jan 1;9(1):727–32.
5. Frieman M, Baric R. Mechanisms of Severe Acute Respiratory Syndrome Pathogenesis and Innate Immunomodulation. Microbiol Mol Biol Rev. 2008 Dec 1;72(4):672–85.
6. Li X, Geng M, Peng Y, Meng L, Lu S. Molecular immune pathogenesis and diagnosis of COVID-19. J Pharm Anal [Internet]. 2020 Mar 5 [cited 2020 Apr 2]; Available from:
7. Rabi FA, Al Zoubi MS, Kasasbeh GA, Salameh DM, Al-Nasser AD. SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far. Pathogens. 2020 Mar;9(3):231.
8. Walls AC, Park Y-J, Tortorici MA, Wall A, McGuire AT, Veesler D. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell [Internet]. 2020 Mar 9 [cited 2020 Apr 1]; Available from:
9. Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun. 2020 Feb 26;102433.
10. Guo Y-R, Cao Q-D, Hong Z-S, Tan Y-Y, Chen S-D, Jin H-J, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status. Mil Med Res. 2020 Mar 13;7(1):11.
11. Jin Y, Yang H, Ji W, Wu W, Chen S, Zhang W, et al. Virology, Epidemiology, Pathogenesis, and Control of COVID-19. Viruses. 2020 Apr;12(4):372.

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corona virus | covid -19 | cause , structure , pathophysiology , symptoms , treatment , prevention

Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV).

Coronavirus disease (COVID-19) is a new strain that was discovered in 2019 and has not been previously identified in humans.

in this lecture we cover about :

why it is called as COVID - 19
Why it is called as SARS - COV 2
structure of conora virus
pathophysiology of corona virus
origin of corona virus
symptoms of covid 19
diagnosis of covid 19
treatment of covid 19
prevention of covid 19

#freemedlectures #coronavirus #covid19
#gocoronago #medicos #sarscov2 #merscov
#corona #virus #coronachina #latestupdateoncorona

COVID-19 Pathogenesis and Risk Factors | Lecturio

In this course, you will be provided with an overview of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2). These lectures will cover the general characteristics of coronaviruses and the origin of the coronavirus disease 2019 (COVID-19).

This video specifically covers:
– Epidemiology
– Risk factors
– Pathogenesis

FREE RESOURCES FOR STUDENTS AND EDUCATORS:
► The COVID-19 Concept Card, which covers the etiology, transmission, epidemiology, clinical presentation, diagnostics, management, and prevention of COVID-19 in one easy-to-digest place:
► The full COVID-19 Video Course, which covers the overview and management of the virus:
► The Studying at Home Guide, which includes some of our best tips for staying focused, being productive, and organizing your study space:
► The Teaching and Learning Continuity Package, with information for institutions to ensure the continuity of teaching through the COVID-19 pandemic:

ABOUT THE PROF:
► Dr. Sean Elliott earned his MD from Columbia University College of Physicians and Surgeons in 1993, followed by a Pediatric Residency at Children’s Memorial Hospital, Northwestern University School of Medicine, and a fellowship in Pediatric Infectious Diseases at St. Louis Children’s Hospital, Washington University School of Medicine. Recruited in 1999 at the University of Arizona College of Medicine, he is now the Professor of Pediatrics and the Associate Chair for the Department of Pediatrics, serving as the Pediatrics Residency Program Director from 2011 to the end of 2017 and as the interim Associate Dean of Curriculum from 2017 through 2019.

LET’S CONNECT:
► Facebook:
► Instagram:

COVID-19: March statistics, Pathogenesis, Clinical Manifestations

In the recent pandemic outbreak of COVID-19, we need to keep ourselves abreast with the current scenario. Its time to be attentive and informed. This video describes the progression of the disease over the last months, the pathogenesis of the disease that enables us to better understand the disease and clinical manifestations that help us to identify the disease. Attempt has been made to assemble updated information from credible sources mentioned in the references at the last of the video.

Corona Virus Pathophysiology

This video will give you a information about the brief explanation of pathophysiology of Corona virus that how Corona virus progression manifest a symptoms.

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Clinical Manifestations of SARS - Coronavirus (SARS-COV)

Severe acute respiratory syndrome (SARS) is a severe form of pneumonia. SARS coronavirus, also known as SARS-CoV, causes severe acute respiratory syndrome (SARS).
Coronaviruses commonly cause infections in both humans and animals. There have been two self-limiting SARS outbreaks to date, which resulted in a highly contagious and potentially life-threatening form of pneumonia.
The virus was present in the masked palm civet. From the civet, it went into a human and then kept spreading by the human to human interaction.
Usually, the coronavirus causes upper respiratory tract infections.
However, the SARS-coronavirus causes lower respiratory tract infection (atypical pneumonia) and viremia.
Dr. Mobeen Syed discusses the clinical manifestation of SARS.
After 2-10 days of exposure to the virus, the patient starts getting chills, malaise, low-grade fever, dry cough, and dyspnea. Usually, it resolves.
If it does not resolve and the patient dies, then the lower respiratory tract shows a lot of alveolar exudates, necrosis, and giant cells.

The following topics have discussed in the video:
* Introduction to SARS
* Transmission of SARS-coronavirus
* Clinical manifestations of SARS
* Clinical features of unresolved SARS
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Introduction to Coronaviruses (SARS, MERS, COVID-19): Hosts, Symptoms, History of SARS and MERS

Lesson on Coronaviruses (SARS, MERS, COVID-19): Viral subtypes, Coronaviruses are a family of RNA viruses that are important viral pathogens in animals and humans. There are four classifications of coronaviruses, with two that are important causes of infections in humans. Coronaviruses can cause both respiratory tract infections and gastrointestinal infections in adults and children. Signs and symptoms are variable dependent on the coronavirus involved. Animals can be both infected and be hosts for the coronaviruses. Transmission of these viruses between species can lead to mutations and development of novel coronaviruses, which can lead to human epidemics and outbreaks. In this lesson, we also discuss a brief history of past human outbreaks and epidemics involving coronaviruses, including severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) and the new Wuhan coronavirus (2019-nCoV).

I hope you find this lesson helpful. If you do, please consider liking, subscribing and clicking the notification bell to help support the channel.

JJ

****EXCLAIMER: The content (ex. images) used in this lesson are used in accordance with Fair Use laws and are intended for educational/teaching purposes only.****

REFERENCES FOR INFORMATION FROM THIS LESSON:

1) The proximal origin of SARS-CoV-2 (2020). Nature Medicine.
2) Review of Bats and SARS (2006). Emerging Infectious Diseases.

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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.

Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.

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*Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.*

I am always looking for ways to improve my lessons! Please don't hesitate to leave me feedback and comments - all of your feedback is greatly appreciated! :)

Thanks for watching! If you found this video helpful, please like and subscribe!
JJ

COVID-19 (Coronavirus Disease 19) March Update- causes, symptoms, diagnosis, treatment, pathology

Watch the Osmosis Video here:

What is COVID-19 (Coronavirus Disease 19)? The coronaviruses that circulate among humans are typically benign, and they cause about a quarter of all common cold illnesses. But occasionally, coronaviruses, like COVID-19, circulate in an animal reservoir and mutate just enough to where they’re able to start infecting and causing disease in humans.

Find our complete video library only on Osmosis Prime:

Hundreds of thousands of current & future clinicians learn by Osmosis. We have unparalleled tools and materials to prepare you to succeed in school, on board exams, and as a future clinician. Sign up for a free trial at

Subscribe to our Youtube channel at

Get early access to our upcoming video releases, practice questions, giveaways, and more when you follow us on social media:
Facebook:
Twitter:
Instagram:

Our Vision: Everyone who cares for someone will learn by Osmosis.
Our Mission: To empower the world’s clinicians and caregivers with the best learning experience possible. Learn more here:

Medical disclaimer: Knowledge Diffusion Inc (DBA Osmosis) does not provide medical advice. Osmosis and the content available on Osmosis's properties (Osmosis.org, YouTube, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.

Coronavirus Infectious Disease 2019 (COVID-19) – March Update | Lecturio

In this video, you will be provided with an overview of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2). This lecture will cover the general characteristics of coronaviruses and the origin of the coronavirus disease 2019 (COVID-19).

FREE RESOURCES FOR STUDENTS AND EDUCATORS:
► The COVID-19 Concept Card, which covers the etiology, transmission, epidemiology, clinical presentation, diagnostics, management, and prevention of COVID-19 in one easy-to-digest place:
► The COVID-19 Video Course, which covers the overview and management of the virus:
► The Studying at Home Guide, which includes some of our best tips for staying focused, being productive, and organizing your study space:
► The Teaching and Learning Continuity Package, with information for institutions to ensure the continuity of teaching through the COVID-19 pandemic:

ABOUT THE PROF:
► Dr. Sean Elliott earned his MD from Columbia University College of Physicians and Surgeons in 1993, followed by a Pediatric Residency at Children’s Memorial Hospital, Northwestern University School of Medicine, and a fellowship in Pediatric Infectious Diseases at St. Louis Children’s Hospital, Washington University School of Medicine. Recruited in 1999 at the University of Arizona College of Medicine, he is now the Professor of Pediatrics and the Associate Chair for the Department of Pediatrics, serving as the Pediatrics Residency Program Director from 2011 to the end of 2017 and as the interim Associate Dean of Curriculum from 2017 through 2019.

LET’S CONNECT:
► Facebook:
► Instagram:

Pathogenesis of SARS-CoV-2

The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The typical generic coronavirus genome is a single strand of RNA. Structurally, SARS-CoV-2 has four main structural proteins including spike (S) glycoprotein, small envelope (E) glycoprotein, membrane (M) glycoprotein, and nucleocapsid (N) protein, and also several accessory proteins. Common symptoms of its infection include fever, cough, fatigue, shortness of breath, and loss of sense of smell. Complications may include pneumonia and acute respiratory distress syndrome. The time from exposure to onset of symptoms is typically around five days but may range from two to fourteen days. There is no known vaccine or specific antiviral treatment. Primary treatment is symptomatic and supportive therapy.

Corona Virus Disease (SAR-CoV-2) Part 1/5 | Epidemiology | Etiology | Pathophysiology

How the Covid-19, namely the Virus SAR-COV2 spreads and causes different symptoms to harm your body. Coronavirus disease (COVID-19) caused by SARS-COV2 is a new disease that was discovered in late December 2019.

It is important to take precautions and main respiratory, body, and mental hygiene.

Topics Covered:
Middle East Respiratory Syndrome (MERS-CoV)
Severe Acute Respiratory Syndrome (SARS-CoV).

Common signs and symptoms:
Dry Cough, Fever, Shortness of breath

Severe cases - You may see Pneumonia, Cardiac Failure, Kidney Failure and even Death.

Resources:



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***Citations**
Harvey, Richard A., Ph. D. Lippincott's Illustrated Reviews: Biochemistry. Philadelphia :Wolters Kluwer Health, 2011.
Kumar, V., Abbas, A. K., Fausto, N., Robbins, S. L., & Cotran, R. S. (2005). Robbins and Cotran pathologic basis of disease. Philadelphia: Elsevier Saunders.
Brenner, G. M., & Stevens, C. W. (2013). Pharmacology. Philadelphia, PA: Elsevier/Saunders.
Katzung, B. G. (2004). Basic & clinical pharmacology. New York: Lange Medical Books/McGraw Hill.
Whalen, K., Finkel, R., & Panavelil, T. A. (2015). Lippincott illustrated reviews: Pharmacology (6th ed.). Philadelphia, PA: Wolters Kluwer.
HALL, J. E., & GUYTON, A. C. (2011). Guyton and Hall textbook of medical physiology. Philadelphia, PA, Saunders Elsevier.
KOEPPEN, B. M., & STANTON, B. A. (2000). Renal physiology. St. Louis, Mosby.
ROSS, M. H., & PAWLINA, W. (2006). Histology: a text and atlas : with correlated cell and molecular biology. Baltimore, MD, Lippincott Wiliams & Wilkins.

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