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COVID-19 | Coronavirus: Treatment, Prognosis, Precautions

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COVID-19 | Coronavirus: Treatment, Prognosis, Precautions

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Ninja Nerds,
What is Corona virus? What is COVID-19? Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). Coronavirus disease (COVID-19) caused by SARS-COV2 is a new strain that was discovered in 2019 and has not been previously identified in humans.
Coronaviruses are zoonotic, meaning they are transmitted between animals and people.  Detailed investigations found that SARS-CoV was transmitted from civet cats to humans and MERS-CoV from camels to humans. Several known coronaviruses are circulating in animals that have not yet infected humans. It is believed that COVID-19 was transmitted from pangolin to humans (current theory).
Common signs of infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death (WHO).
Ninja Nerd Lectures has compiled the most up to date and recent data on COVID-19 as of March 15, 2020. Please follow along with this lecture to understand the treatment, prognosis, and precautions for COVID-19 (current as of 3/15/2020).
As new information and research is published we will continue to provide updates on COVID-19 and ensure all of our viewers are kept up to date on the most recent data.

REFERENCES: World Health Organization (WHO), Centers for Disease Control and Prevention (CDC).

REFERENCES: World Health Organization (WHO), Centers for Disease Control and Prevention (CDC).


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COVID-19 ( Coronavirus Disease 19) - causes, symptoms, diagnosis, treatment, precautions

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COVID-19 ( Coronavirus Disease 19) - causes, symptoms, diagnosis, treatment, precautions
In this video you'll learn what is coronavirus, what are the causes and symptoms of it? and how you can protect yourself from corona virus.

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COVID-19 (Coronavirus Disease 19) May Update- causes, symptoms, diagnosis, treatment, pathology

Watch the Osmosis Video here:

What is COVID-19 (Coronavirus Disease 19)? The coronaviruses that circulate among humans are typically benign, and they cause about a quarter of all common cold illnesses. But occasionally, coronaviruses, like COVID-19, circulate in an animal reservoir and mutate just enough to where they’re able to start infecting and causing disease in humans.

Find our complete video library only on Osmosis Prime:

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Medical disclaimer: Knowledge Diffusion Inc (DBA Osmosis) does not provide medical advice. Osmosis and the content available on Osmosis's properties (Osmosis.org, YouTube, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.
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Coronavirus in Tamil | Dr. V Ramasubramanian | Apollo Hospitals

Know more about Coronavirus in Tamil by Dr. V Ramasubramanian from Apollo Hospitals, Chennai. Dr. V Ramasubramanian is a senior consultant in the Department of infectious disease and tropical medicine.
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Coronavirus (COVID19) Symptoms and Treatment - (Update from China and US)

The video includes an update on the most common new coronavirus (COVID-19 virus) symptoms out of a Chinese report and treatment guidelines from the World Health Organisation (WHO).

Visit and find simple and practical information from reliable international sources regarding the current outbreak of coronavirus disease (COVID-19).

Coronavirus Youtube playlist:

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Video Sources:
- WHO:
- CCDC:

#Coronavirus #CoronavirusSymptoms #CoronavirusTreatment #China #Corona #CoronaVirusUpdate #Coronavirusoutbreak #coronavirusliveupdate #COVID_19 #Coronavid19 #PreventCOVID #Potential #RealWorldEd #OnlineLearning #Empower #Educate #Engage #EmpowermentPlatform #COVID19Treatment #COVID19Symptoms

Coronavirus: Symptoms, Precautions and Prevention

As the world gets together to curb the coronavirus pandemic, a majority of cases are now being recorded in India too. Being equipped with the information to beat coronavirus is half the fight. Watch the video to understand everything about the #Coronavirus and how to stay safe during this health crisis.
Stay informed to stay safe. #SayNoToCovid19

Drugs used for COVID-19 / Treatment of COVID-19 or Coronavirus disease as per the latest Guidelines

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Drugs used for COVID-19 / Treatment of COVID-19 or Coronavirus disease as per the latest Guidelines

Remdesivir, Chloroquine/ hydroxychloroquine, Lopinavir/ritonavir and Tocilizumab for COVID-19

Remdesivir
Remdesivir is an investigational intravenous drug with broad antiviral activity that inhibits viral replication through premature termination of RNA transcription and has in-vitro activity against SARS-CoV-2 and in-vitro and in-vivo activity against related betacoronaviruses .
Blocks RNA-dependent polymerases
Several randomized trials are underway to evaluate the efficacy of remdesivir for moderate or severe COVID-19
Its clinical efficacy is not well understood.

Hydroxychloroquine and chloroquine are oral prescription drugs that have been used for treatment of malaria and certain inflammatory conditions. Chloroquine has been used for malaria treatment and chemoprophylaxis, and hydroxychloroquine is used for treatment of rheumatoid arthritis, systemic lupus erythematosus and porphyria cutanea tarda. Both drugs have in-vitro activity against SARS-CoV, SARS-CoV-2, and other coronaviruses, with hydroxychloroquine having relatively higher potency against SARS-CoV-2
Both chloroquine and hydroxychloroquine have been reported to inhibit SARS-CoV-2 in vitro, although hydroxychloroquine appears to have more potent antiviral activity .
Use of chloroquine is included in treatment guidelines from China's National Health Commission and was reportedly associated with reduced progression of disease and decreased duration of symptoms . However, primary data supporting these claims have not been published .
Other published clinical data on either of these agents are limited. In an open-label study of 36 patients with COVID-19, use of hydroxychloroquine (200 mg three times per day for 10 days) was associated with a higher rate of undetectable SARS-CoV-2 RNA on nasopharyngeal specimens at day 6 compared with no specific treatment (70 versus 12.5 percent) . In this study, the use of azithromycin in combination with hydroxychloroquine appeared to have additional benefit, but there are methodologic concerns about the control groups for the study, and the biologic basis for using azithromycin in this setting is unclear.


Clinical trails explains that

Treatment of Moderate to Severe Coronavirus Disease (COVID-19) in Hospitalized Patients
Estimated Study Completion Date : July 2021
• Lopinavir/ritonavir
• Hydroxychloroquine sulfate
• Baricitinib (janus kinase inhibitor)
• Sarilumab (anti-IL-6 receptor)
Tocilizumab – Treatment guidelines from China's National Health Commission include the IL-6 inhibitor tocilizumab for patients with severe COVID-19 and elevated IL-6 levels; the agent is being evaluated in a clinical trial
Tocilizumab is under investigation for COVID-19 Pneumonia - Drug: Tocilizumab Injection , present in Phase 2 clinical trials
Inhibition of IL-6 receptors by tocilizumab leads to a reduction in cytokine and acute phase reactant



Lopinavir-ritonavir – Lopinavir-ritonavir appears to have little to no role in the treatment of SARS-CoV-2 infection. This combined protease inhibitor, which has primarily been used for HIV infection, has in vitro activity against the SARS-CoV and appears to have some activity against MERS-CoV in animal studies . However, there was no difference in time to clinical improvement or mortality at 28 days in a randomized trial of 199 patients with severe COVID-19 given lopinavir-ritonavir (400/100 mg) twice daily for 14 days in addition to standard care versus those who received standard of care alone



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The expanded access program for the United States is under rapid development. Further information is available at: icon

#covid19treatment #drugsusedincovid19 #treatmentforcovid19 #treatmentforcoronavirusdisease #coronavirusdiseasetreatment #medicineforcovid19 #drugsusedincovid19patients #covid19treatment

How Are Doctors Treating COVID-19? | UC San Diego Health

Remdesivir, chloroquine/hydroxychloroquine…lots of drugs are being touted as “cures” for COVID-19. But what are doctors actually using to treat the virus in the clinic? In this video, you can learn more about current treatments and new clinical trials – including a trial at UC San Diego.

This video was filmed on April 16, 2020. Preliminary clinical trial results have indicated that chloroquine/hydroxychloroquine are not very effective at treating the SARS-CoV-2 virus, and can lead to serious negative side effects. Another preliminary clinical trial at University of Chicago Medicine has shown promising results for Remdesivir as a potential treatment.

Learn more about the status of treatments ➡️bit.ly/34ZQHHq
For the latest information from UC San Diego Health regarding COVID-19, please visit

Recognizing Day to Day Signs and Symptoms of Coronavirus

Based on Guidelines by Singapore Health Ministry. This is just a guideline, if you feel ill please contact your health provider immediately.

Primary sources:





COVID-19 (SARS Coronavirus 2) - timeline, pathophysiology (ARDS), coronavirus life cycle, treatment

The World health organization (WHO) has declared COVID-19 a pandemic. COVID 19 stands for coronavirus disease 2019 and is caused by the severe acute respiratory syndrome coronavirus 2.

Coronaviruses are a large family of viruses that are common in people and many different species of animals including cats and bats. Common human coronavirus typically causes a URTI, like the common cold. Most people get infected with one or more of these viruses at some point in their lives. The human coronavirus infection typically resolves on its own with basic rest while feeling miserable.

Rarely, the coronaviruses that infect animals can evolve and become a new human coronavirus which then infect and spread between people. Important examples of these type of coronavirus include severe acute respiratory syndrome coronavirus, SARS CoV for short in 2003 and Middle East respiratory syndrome coronavirus also known as MERS.
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COVID-19 | Coronavirus: Epidemiology, Pathophysiology | APRIL UPDATE

Ninja Nerds,
Join us for our lecture on COVID-19 where Ninja Nerd Science will go into detail on the virology, epidemiology, and pathophysiology/pathology of COVID-19. This is our April update on our previous lecture to keep all of our viewers informed on the new research and publications that have been released on COVID-19. Please be aware— This lecture is up to date as of April 17, 2020.

Coronaviruses are a large family of viruses which may cause illness in animals or humans.  In humans, several coronaviruses are known to cause respiratory infections ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). The most recently discovered coronavirus causes coronavirus disease COVID-19.

COVID-19 is the infectious disease caused by the most recently discovered coronavirus. This new virus and disease were unknown before the outbreak began in Wuhan, China, in December 2019.

The most common symptoms of COVID-19 are fever, tiredness, and dry cough. Some patients may have aches and pains, nasal congestion, runny nose, sore throat or diarrhea. These symptoms are usually mild and begin gradually. Some people become infected but don’t develop any symptoms and don't feel unwell. Most people (about 80%) recover from the disease without needing special treatment. Around 1 out of every 6 people who gets COVID-19 becomes seriously ill and develops difficulty breathing. Older people, and those with underlying medical problems like high blood pressure, heart problems or diabetes, are more likely to develop serious illness. People with fever, cough and difficulty breathing should seek medical attention.

World Health Organization (WHO) | 8 April 2020

REFERENCES | We have a complete list of our references in AMA format on our Facebook & Instagram!

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Dr. Rajiv Dang on Precautions and Symptoms of Coronavirus

Here’s Dr. Rajiv Dang , advising you to be more aware and cautious about Coronavirus. This virus is causing a lot of panic as it is similar to other respiratory infections.

COVID-19 (Coronavirus Disease 19) March Update- causes, symptoms, diagnosis, treatment, pathology

Watch the Osmosis Video here:

What is COVID-19 (Coronavirus Disease 19)? The coronaviruses that circulate among humans are typically benign, and they cause about a quarter of all common cold illnesses. But occasionally, coronaviruses, like COVID-19, circulate in an animal reservoir and mutate just enough to where they’re able to start infecting and causing disease in humans.

Find our complete video library only on Osmosis Prime:

Hundreds of thousands of current & future clinicians learn by Osmosis. We have unparalleled tools and materials to prepare you to succeed in school, on board exams, and as a future clinician. Sign up for a free trial at

Subscribe to our Youtube channel at

Get early access to our upcoming video releases, practice questions, giveaways, and more when you follow us on social media:
Facebook:
Twitter:
Instagram:

Our Vision: Everyone who cares for someone will learn by Osmosis.
Our Mission: To empower the world’s clinicians and caregivers with the best learning experience possible. Learn more here:

Medical disclaimer: Knowledge Diffusion Inc (DBA Osmosis) does not provide medical advice. Osmosis and the content available on Osmosis's properties (Osmosis.org, YouTube, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.

COVID-19 | Coronavirus: Epidemiology, Pathophysiology, Diagnostics

HELP US GET OUR OWN FILMING STUDIO --

Ninja Nerds,
What is Corona virus? What is COVID-19? Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). Coronavirus disease (COVID-19) caused by SARS-COV2 is a new strain that was discovered in 2019 and has not been previously identified in humans.
Coronaviruses are zoonotic, meaning they are transmitted between animals and people.  Detailed investigations found that SARS-CoV was transmitted from civet cats to humans and MERS-CoV from camels to humans. Several known coronaviruses are circulating in animals that have not yet infected humans. It is believed that COVID-19 was transmitted from pangolin to humans (current theory).
Common signs of infection include respiratory symptoms, fever, cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death (WHO, 2020).
Ninja Nerd Lectures has compiled the most up to date and recent data on COVID-19 as of March 15, 2020. Please follow along with this lecture to understand the origin and zoonosis of COVID-19, the routes of transmission, epidemiology (current as of 3/15/2020), pathophysiology, and diagnostic tests used to identify COVID-19.
As new information and research is published we will continue to provide updates on COVID-19 and ensure all of our viewers are kept up to date on the most recent data.

SUPPORT US! paypal.me/ninjanerdscience

REFERENCES: World Health Organization (WHO), Centers for Disease Control and Prevention (CDC).


Support us by purchasing apparel and donating to our PayPal or Patreon! ????

--Become a Patron of ours and receive the final, high resolution photo of the lecture!

FUNDING

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Teespring |

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INSTAGRAM |


ALSO, check out our Medical channel | Ninja Nerd Medicine!

How to prevent Coronavirus | Dr. Ratnamani | Apollo Hospitals

Know how to prevent #Coronavirus with Dr. Ratnamani from Apollo Hospitals, Hyderabad .#nCoV #WuhanVirus #ApolloHospitals
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COVID-19 (Coronavirus Disease 19) April Update- causes, symptoms, diagnosis, treatment, pathology

Watch the Osmosis Video here:

What is COVID-19 (Coronavirus Disease 19)? The coronaviruses that circulate among humans are typically benign, and they cause about a quarter of all common cold illnesses. But occasionally, coronaviruses, like COVID-19, circulate in an animal reservoir and mutate just enough to where they’re able to start infecting and causing disease in humans.

Find our complete video library only on Osmosis Prime:

Hundreds of thousands of current & future clinicians learn by Osmosis. We have unparalleled tools and materials to prepare you to succeed in school, on board exams, and as a future clinician. Sign up for a free trial at

Subscribe to our Youtube channel at

Get early access to our upcoming video releases, practice questions, giveaways, and more when you follow us on social media:
Facebook:
Twitter:
Instagram:

Our Vision: Everyone who cares for someone will learn by Osmosis.
Our Mission: To empower the world’s clinicians and caregivers with the best learning experience possible. Learn more here:

Medical disclaimer: Knowledge Diffusion Inc (DBA Osmosis) does not provide medical advice. Osmosis and the content available on Osmosis's properties (Osmosis.org, YouTube, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.

Home care for suspected and mild cases of COVID-19

As COVID-19 continues to spread, WHO recommends that all laboratory confirmed cases be isolated and cared for in a health care facility. For those who can only receive care at home, this video provides simple advice on how this can be done while minimizing the spread of infection to other family members. For more detailed information please read this WHO guidance document:

What are the potential treatments for coronavirus (COVID-19)? | Wellcome

Researchers are taking a wide range of approaches to find a safe and effective treatment for COVID-19, but what are they?

Nick Cammack, Wellcome’s COVID-19 Therapeutics Accelerator Lead, explains more.

Find out more about research into COVID-19 treatments:

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COVID-19 Insights: COVID-19 (by SARS-COV-2/Coronavirus) Signs, Symptoms and Management

Diseases lasts 2 weeks on average in 81% of the population
In 14% that become serious it can go on from 2 weeks to 6 weeks
in 5% critical cases it can go from 2 to 8 weeks

Asymptomatic
Youngsters
And, incubation time
Median incubation time is 5.1 days

Symptoms at onset*:
Fever (98%),
Dry cough (76%)
Fatigue & myalgia (44%)
Sputum production (28%)
Headache (8%)
Haemoptysis (5%)
Diarrhoea (3%)
Subsequent symptoms: dyspnoea (25%)

Mild cases: The majority (81%) of these coronavirus disease cases were mild cases. Mild cases include all patients without pneumonia or cases of mild pneumonia.

Severe cases: This includes patients who suffered from shortness of breath, respiratory frequency ≥ 30/minute, blood oxygen saturation ≤93%, PaO2/FiO2 ratio lesser than 300, and/or lung infiltrates greater than 50% within 24–48 hours. 

PaO2 (partial pressure of oxygen)
FiO2 (fraction of inspired oxygen)
PaO2/FiO2 is called Horowitz index, or Carrico index and the PF ratio


Critical cases: Critical cases include patients who suffered respiratory failure, septic shock, and/or multiple organ dysfunction or failure.



Management
Supportive management

Antivirals for COVID-19
According to the WHO
There are no known effective antivirals for coronavirus infections.
• Various candidates with potential anti-nCoV activity are being evaluated for clinical trial protocols (see module 15).
• Use of unregistered or unproven therapeutics for nCoV should be done under strict monitoring and ethical approval.
– Use WHO Monitored Emergency Use of Unregistered Interventions (MEURI) framework (see module 15)

Remdesivir




Remdesivir cripples an enzyme called RNA polymerase that is used by many viruses to copy themselves; it does not specifically target SARS-CoV-2, the virus that causes COVID-19.

Article being critical of the remdesivir efficacy



Chloroquine
Antimalarial and HIV medicine
Makes the cell organelle less acidic (raises their pH which interferes with the virus replication.)
It also interferes with the terminal glycosylation of the ACE2 receptor negatively influencing the virus receptor binding

COVID-19: Infectious Disease Precautions | Lecturio

In this course, you will learn about Safety for Health Care Professionals (HCPs) in the wake of Coronavirus disease 2019 (SARS-CoV 2).

IN THIS VIDEO, you will learn about the difference between contact, droplet, and airborne precautions.

FREE RESOURCES FOR STUDENTS AND EDUCATORS:
► The COVID-19 Concept Card, which covers the etiology, transmission, epidemiology, clinical presentation, diagnostics, management, and prevention of COVID-19 in one easy-to-digest place:
► The full COVID-19 Video Course, which includes an overview and management of the virus, safety for healthcare professionals, and a clinical case:
► The Studying at Home Guide, which includes some of our best tips for staying focused, being productive, and organizing your study space:
► The Teaching and Learning Continuity Package, with information for institutions to ensure the continuity of teaching through the COVID-19 pandemic:

ABOUT THE PROF:
► THE PROF: Rhonda Lawes is a Certified Nurse Educator (CNE) and Assistant Professor at the University of Oklahoma. She worked as a nurse manager at the Saint Francis Hospital and the Broken Arrow Medical Center. She has completed her Ph.D. in Educational Psychology at Oklahoma State University.

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