COVID-19 Animation: What Happens If You Get Coronavirus?
This video 3D animation on COVID-19: What Happens If You Get Coronavirus is a collaboration between Nucleus Medical Media and our friends at the What If Channel. To watch super interesting hypothetical scenarios on the human body, humanity, the planet and the cosmos, please visit the What If Channel at
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3D Animation: SARS-CoV-2 virus transmission leading to COVID-19
Thanks to the brilliant team at Helix Animation for this 3D animation outlining the most common ways of transmitting the coronavirus SARS=CoV-2 based on the latest relevant scientific research available (March 2020).
Please note that the knowledge of this infectious disease and its transmission, as well as on this novel coronavirus, is still incomplete and evolving. Facts may change over time as the outbreak is ongoing with the latest updates found at:
As typical for 3D visualizations, the overall virus representation is an artistic depiction, and the surface proteins density and distribution have been simplified, in order the entire audience to easily grasp the most prominent features of this virus.
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How Community Spread Happens Fast - Coronavirus (COVID-19) Updated 4-7-2020
UPDATED VERSION 11/24/2020:
Justin, a millennial, brings a box of donuts to the office and unknowingly spreads the coronavirus to his colleagues who further spread throughout the community. A motion graphic animation to show how healthy people are so crucial in curbing the spread and how community spread of Coronavirus (COVID-19) occurs - sometimes unknowingly by seemingly healthy people spreading the disease rapidly in socially dense environments.
Coronavirus outbreak (covid 19) explained through 3D Medical Animation
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The 2019 nCoV Novel Coronavirus is fast threatening to become a pandemic. This 3D medical animation explains the story so far, covering what is a pandemic, current rates of infection and tips to protect against infections. It also delves into the biology and mechanism of action MoA that coronavirus uses to infect and destroy human cells. Though the exact MoA for this coronavirus is not known.
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The Coronavirus Explained & What You Should Do
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In December 2019 the Chinese authorities notified the world that a virus was spreading through their communities. In the following months it spread to other countries, with cases doubling within days. This virus is the “Severe acute respiratory syndrome-related coronavirus 2”, that causes the disease called COVID19, and that everyone simply calls Coronavirus.
What actually happens when it infects a human and what should we all do?
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Understanding the Virus that Causes COVID-19, Animation
Overview of coronavirus family, origin of SARS-CoV-2, viral structure and life cycle, pathophysiology. This video is available for instant download licensing here :
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Coronaviruses are a large family of enveloped, RNA viruses. There are 4 groups of coronaviruses: alpha and beta, originated from bats and rodents; and gamma and delta, originated from avian species. Coronaviruses are responsible for a wide range of diseases in many animals, including livestock and pets. In humans, they were thought to cause mild, self-limiting respiratory infections until 2002, when a beta-coronavirus crossed species barriers from bats to a mammalian host, before jumping to humans, causing the Severe Acute Respiratory Syndrome, SARS, epidemic. More recently, another beta-coronavirus is responsible for the serious Middle East Respiratory Syndrome, MERS, started in 2012. The novel coronavirus responsible for the Coronavirus Disease 2019 pandemic, COVID-19, is also a beta-coronavirus. The genome of the virus is fully sequenced and appears to be most similar to a strain in bats, suggesting that it also originated from bats. The virus is also very similar to the SARS-coronavirus and is therefore named SARS-coronavirus 2, SARS-CoV 2. At the moment, it’s not yet clear if the virus jumped directly from bats to humans, or if there is a mammalian intermediate host.
Coronavirus genome is a large, single-stranded, positive-sense RNA molecule that contains all information necessary for the making of viral components. The RNA is coated with structural proteins, forming a complex known as nucleocapsid. The nucleocapsid is enclosed in an envelope, which is basically a LIPID membrane with embedded proteins. From the envelope, club-like spikes emanate, giving the appearance of a crown. This is where the “corona” name came from.
The integrity of the envelope is essential for viral infection, and is the Achilles’ heel of the virus, because the lipid membrane can easily be destroyed by lipid solvents such as detergents, alcohol and some disinfectants. In fact, enveloped viruses are the easiest to inactivate when they are outside a host.
In order to infect a host cell, the spikes of the virus must BIND to a molecule on the cell surface, called a receptor. The specificity of this binding explains why viruses are usually species specific – they have receptors in certain species, and not others. Host jumping is usually triggered by mutations in spike proteins which change them in a way that they now can bind to a receptor in a new species.
The novel coronavirus appears to use the same receptor as SARS-coronavirus for entry to human cells, and that receptor is the angiotensin-converting enzyme 2, ACE2. Infection usually starts with cells of the respiratory mucosa, then spreads to epithelial cells of alveoli in the lungs.
Receptor binding is followed by fusion of the viral membrane with host cell membrane, and the release of nucleocapsid into the cell. The virus then uses the host machinery to replicate, producing viral RNAs and proteins. These are then assembled into new viral particles, called virions, by budding into intracellular membranes. The new virions are released and the host cell dies.
Uncontrolled growth of the virus destroys respiratory tissues, producing symptoms. Infection triggers the body’s inflammatory response, which brings immune cells to the site to fight the virus. While inflammation is an important defense mechanism, it may become excessive and cause damage to the body’s own tissues, contributing to the severity of the disease. In an otherwise healthy person, there is a good chance that the virus is eventually eliminated and the patient recovers, although some may require supportive treatments. On the other hand, people with weakened immune system or underlying chronic diseases may progress to severe pneumonia or acute respiratory distress syndrome, which can be fatal.
How COVID-19 Affects the Body
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COVID-19 is the short name for the disease known as novel coronavirus disease 2019. Coronaviruses are a large group of similar viruses. Some are known to infect humans, such as SARS-CoV and MERS-CoV. The one that causes COVID-19 is called SARS-CoV-2. All coronaviruses are named for the crown-like “spikes” that cover their surface, called spike, or “S,” proteins. Inside the virus, genetic material, called RNA, is made up of genes. Genes carry the information to make more copies of the virus. The virus can infect you if it enters your mouth, nose, or lungs. Inside your body, the S protein of the virus locks to a receptor on the surface of one of your cells. This can trigger the virus to enter the cell in a couple of ways. It may cause the virus to fuse with the cell surface, then release its genes into the cell. Or, the cell may pull the virus inside by enclosing it in a sac. Once inside, the virus can fuse to the sac and release its genes. Next, the genes use a structure in your cell, called a ribosome, to make new copies of the virus. The new viruses travel to the surface of the cell. There, they can leave to infect more cells. In the meantime, viral S proteins left on the surface of the infected cell can cause it to fuse with nearby healthy cells, forming a giant cell. This may be another way for the virus to spread between cells. People may be infected with COVID-19 for two to fourteen days before symptoms appear. The three main symptoms of COVID-19 are: a fever, cough, and shortness of breath. Other symptoms may include: tiredness, body aches, stuffy nose, sore throat, diarrhea and vomiting, loss of appetite, and loss of smell. Most people have a mild illness and can recover at home. Some people who have the virus may not get sick at all or may show no symptoms. But, if you have trouble breathing, or any other symptoms that are severe, call your doctor or the emergency room. They will tell you what to do. For most people who have the virus, the risk for serious illness is thought to be low. People sixty-five years and older may have a higher risk for serious illness. And, people of any age may be at high-risk if they have underlying conditions, such as: chronic lung disease or asthma; serious heart conditions; diabetes; severe obesity; chronic kidney disease, and liver disease. High-risk groups also include people with a weakened immune system, including: those on certain medications, such as corticosteroids; people in cancer treatment; and those with HIV or AIDS. Even if you aren’t in a high-risk group, it’s important to practice social distancing, which means keeping at least two meters, or six feet, between you and other people. This helps prevent infections and serious illness in others as well as yourself. For up-to-date information about COVID-19 and other ways to prevent its spread, visit the CDC website.
HOW DOES COVID-19 AFFECT THE BODY?
Coronaviruses (CoV) are a family of viruses that cause sicknesses like the common cold, as well as more severe diseases, such as Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome. A novel coronavirus (nCoV) is a new strain – one that hasn’t previously been recognized in humans.
Coronaviruses cause diseases in mammals and birds. A zoonotic virus is one that is transmitted between animals and people. When a virus circulating in animal populations infects people, this is termed a “spillover event”.
How does CoVID-19 affect the body? The virus is fitted with protein spikes sticking out of the envelope that forms the surface and houses a core of genetic material. Any virus that enters your body looks for cells with compatible receptors – ones that allow it to invade the cell. Once they find the right cell, they enter and use the cell’s replication machinery to create copies of themselves. It is likely that COVID-19 uses the same receptor as SARS – found in both lungs and small intestines.
It is thought that CoVID-19 shares many similarities with SARS, which has three phases of attack: viral replication, hyper-reactivity of the immune system, and finally pulmonary destruction. Early on in infection, the coronavirus invades two types of cells in the lungs – mucus and cilia cells. Mucus keeps your lungs from drying out and protects them from pathogens. Cilia beat the mucus towards the exterior of your body, clearing debris – including viruses! – out of your lungs. Cilia cells were the preferred hosts of SARS-CoV, and are likely the preferred hosts of the new coronavirus. When these cells die, they slough off into your airways, filling them with debris and fluid. Symptoms include a fever, cough, and breathing difficulties. Many of those infected get pneumonia in both their lungs.
Enter the immune system. Immune cells recognize the virus and flood into the lungs. The lung tissue becomes inflamed. During normal immune function, the inflammatory process is highly regulated and is confined to infected areas. However, sometimes the immune system overreacts, and this results in damage to healthy tissue. More cells die and slough off into the lungs, further clogging them and worsening the pneumonia.
As damage to the lungs increases, stage three begins, potentially resulting in respiratory failure. Patients that reach this stage of infection can incur permanent lung damage or even die. We see the same lesions in the lungs of those infected by the novel coronavirus as those with SARS. SARS creates holes in the lungs, so they look honeycomb-like. This is probably due to the aforementioned over-reactive immune response, which affects tissue both infected and healthy and creates scars that stiffen the lungs. As such, some patients may require ventilators to aid breathing.
The inflammation also results in more permeable alveoli. This is the location of the thin interface of gas exchange, where your lungs replace carbon dioxide in your blood with fresh oxygen you just inhaled. Increased permeability causes fluid to leak into the lungs. This decreases the lungs’ ability to oxygenate blood, and in severe cases, floods them so that you become unable to breathe. Sometimes, this can be fatal.
The immune system’s over-reaction can also cause another kind of damage. Proteins called cytokines are the immune system’s alarm system, recruiting immune cells to the infection site. Over-production of cytokines can result in a cytokine storm, where there is large-scale inflammation in the body. Blood vessels become more permeable and fluid seeps out. This makes it difficult for blood and oxygen to reach the rest of the body and can result in multi-organ failure. This has happened in the most severe cases of CoVid-19. Although there are no specific treatments for coronaviruses, symptoms can be treated through supportive care. Also, vaccines are currently in development.
What can you do to protect yourself from CoVid-19? Basic protocol comes down to regular hand washing, avoiding close contact with anyone coughing or sneezing, avoiding unnecessary contact with animals, washing hands after contact with animals, thoroughly cooking meat and eggs prior to consumption, and covering your mouth and nose while coughing or sneezing. Respiratory viruses are typically transmitted via droplets in sneezes or coughs of those infected, so preventing their travel stops the spread of disease.
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Corona Virus Disease / COVID-19: Sahi aur Galath coronavirus disease ke baare me ( HINDI ) - Part 1
How to Obtain a Nasopharyngeal Swab Specimen for COVID-19 suspected patients
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Corona Virus Disease / COVID-19: Facts and figures for Public Awareness
How COVID-19 Spreads
The virus is thought to spread mainly from person-to-person.
Between people who are in close contact with one another (within about 6 feet).
Through respiratory droplets produced when an infected person coughs or sneezes.
These droplets can land in the mouths or noses of people who are nearby or possibly be inhaled into the lungs.
Can someone spread the virus without being sick?
People are thought to be most contagious when they are most symptomatic (the sickest).
Some spread might be possible before people show symptoms; there have been reports of this occurring with this new coronavirus, but this is not thought to be the main way the virus spreads.
Spread from contact with contaminated surfaces or objects
It may be possible that a person can get COVID-19 by touching a surface or object that has the virus on it and then touching their own mouth, nose, or possibly their eyes, but this is not thought to be the main way the virus spreads.
How easily the virus spreads
How easily a virus spreads from person-to-person can vary. Some viruses are highly contagious (spread easily), like measles, while other viruses do not spread as easily. Another factor is whether the spread is sustained, spreading continually without stopping.
Should I wear a respirator in public?
CDC does not recommend the routine use of respirators outside of workplace settings (in the community). Most often, spread of respiratory viruses from person-to-person happens among close contacts (within 6 feet). CDC recommends everyday preventive actions to prevent the spread of respiratory viruses, such as avoiding people who are sick, avoiding touching your eyes or nose, and covering your cough or sneeze with a tissue. People who are sick should stay home and not go into crowded public places or visit people in hospitals. Workers who are sick should follow CDC guidelines and stay home when they are sick.
What is a respirator?
A respirator is a personal protective device that is worn on the face or head and covers at least the nose and mouth. A respirator is used to reduce the wearer’s risk of inhaling hazardous airborne particles (including infectious agents), gases or vapors. Respirators, including those intended for use in healthcare settings, are certified by the CDC/NIOSH.
What is an N95 filtering facepiece respirator (FFR)?
An N95 FFR is a type of respirator which removes particles from the air that are breathed through it. These respirators filter out at least 95% of very small (0.3 micron) particles. N95 FFRs are capable of filtering out all types of particles, including bacteria and viruses.
Checklist to Get Ready
As a family, you can plan and make decisions now that will protect you and your family during a COVID-19 outbreak.
Stay informed and in touch
Get up-to-date information about local COVID-19 activity from public health officials
Ask your neighbors what their plan includes.
Create a list of local organizations you and your household can contact in case you need access to information, healthcare services, support, and resources.
Create an emergency contact list including family, friends, neighbors, carpool drivers, healthcare providers, teachers, employers, the local public health department, and other community resources.
Prepare for possible illness
Consider members of the household that may be at greater risk such as older adults and people with severe chronic illnesses.
Choose a room in your house that can be used to separate sick household members from others.
Take everyday preventive steps
Wash your hands frequently
Avoid touching your eyes, nose, and mouth.
Stay home when you are sick.
Cover your cough or sneeze with a tissue, then throw the tissue in the trash.
Clean and disinfect frequently touched objects and surfaces Be prepared if your child’s school or childcare facility is temporarily dismissed or for potential changes at your workplace.
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3D Animation: How Do I Protect Myself From Coronavirus, COVID-19?
COVID-19 is a disease caused by a new coronavirus that was identified in China. It is thought to spread from person to person when people are close together, and through droplets produced when a sick person coughs or sneezes.
Currently, there is no treatment for COVID-19. The best way to keep yourself from getting sick is to avoid being exposed to the virus. One way to protect yourself is to clean your hands often. Wash your hands often with soap and water for at least twenty seconds. If soap and water aren’t available, use a hand sanitizer. It should contain at least sixty percent alcohol. Avoid touching your face with unwashed hands. Another way to protect yourself is to avoid close contact with other people. This includes avoiding contact with sick people. And, put distance between yourself and others by staying home as much as possible. If you have to go out, aim to keep a minimum of six feet between yourself and others when possible. For more information, visit the website for the Centers for Disease Control.
Symptoms of Coronavirus | COVID-19 | #aumsum #kids #science #education #children
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Novel coronavirus or 2019-nCoV is a new strain of coronavirus which was first detected in Wuhan, China in December 2019.
The disease caused by novel coronavirus is named as COVID-19.
Fever, tiredness and dry cough are the most common symptoms of COVID-19. Some infected people may also experience aches and pains, nasal congestion, runny nose, sore throat or diarrhea.
Symptoms of COVID-19 are usually mild and begin gradually. Also surprisingly, some infected people don't even develop symptoms and don't feel unwell.
It is estimated that more than 80% of people recover without the need of special treatment. But it is also estimated that 1 out of 6 people suffering from COVID-19 will become seriously ill and will develop difficulty breathing. Also, people with underlying medical problems like high blood pressure, heart problems or diabetes as well as older people are more likely to develop serious illness.
It is advised by WHO that people with fever, cough and difficulty breathing should seek medical attention.
Coronavirus Animation: High Impact Demonstrates How COVID-19 Impacts the Body
Coronavirus, which causes COVID-19, originated in the city of Wuhan, China, and has since spread across the globe at an alarming rate. We produced this 3D coronavirus animation to show how COVID-19 is believed to be transmitted while educating the public on the symptoms that may be caused by COVID-19.
Follow the World Health Organization for updates about the international spread of Coronavirus and how to protect yourself from COVID-19:
Follow the U.S. Centers for Disease Control and Prevention to learn how the coronavirus outbreak is currently spreading across the United States, and recommendations for improving your safety and resilience.
If you are currently leading government or private efforts to combat the coronavirus outbreak and you think our visualizations could help in your mission to educate the public or relevant stakeholders about this virus, we encourage you to visit our website, view some of our medical work, and reach out to learn how we can help.
Staying Safe When COVID-19 Strikes
What should you do if you experience symptoms of COVID-19? This short animated video from Stanford Medicine's Maya Adam illustrates practices for getting well and keeping others healthy.
Get the latest news on COVID-19 testing, treatment, and tracking data:
Stopping the spread of Covid-19: animation for BAME primary school pupils
West London NHS Charitable Fund has funded two animations, for children from Black & Minority Ethnic (BAME) backgrounds, on how they can stay well and prevent the spread of Covid-19.
These animations were co-produced by a team of young people, educational specialists, equality leads, and youth and community advocates - and are being shown in schools across West London.
The second animation is aimed at BAME secondary school pupils:
CONNECT WITH US
In this video we will talk about the following topics:
1. What is the difference between SARS-CoV-2, 2019-nCoV and COVID-19?
2. Why is SARS-CoV-2 different from other Coronaviruses?
3. Why is social distancing important?
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The Great Race: A COVID-19 Story
Wear a mask. Together we are stronger.
Scientists are encouraging everyone to wear masks to control the spread of COVID-19. For additional info, Stanford Medicine experts discuss evidence that informed the World Health Organization’s recommendations and explain how you can help flatten the curve of COVID-19 infections:
This video was created for Stanford Medicine by Maya Adam
Animation: Matt Torode
Special Thanks: Russ Haan, Jennifer Gates, Marsha Griffin, Ryan Matlow, Amy Price and Yvonne A. Maldonado
What happens when you're infected with the COVID-19 coronavirus? | DW News
The vast majority of patients with the new coronavirus recover successfully without needing serious medical attention. So how many people recover – and what helps?
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How Contagious is COVID-19? (Transmission, Spread, and R0)
Transmission of SARS-CoV-2 occurs via droplet transmission, contact transmission, and aerosol transmission. Droplet transmission occurs when respiratory droplets produced when an infected person coughs or sneezes are inhaled by a person nearby. Contact transmission occurs when a person touches a contaminated surface and then their mouth, nose, or eyes. Aerosol transmission occurs when respiratory droplets containing the virus mix into the air and then are inhaled. COVID-19 is stable for up to 24 hours on cardboard, 2-3 days on plastic and stainless steel and up to three hours in aerosols, which include fog, mist, dust, air pollutants, and smoke. Therefore, it is possible to get infected by touching contaminated objects or through the air.
The incubation period is the time between infection and symptom onset for an illness. Estimates for COVID-19’s incubation period vary from 2-14 days, but it is generally assumed to be around 5 days. There is more debate about the latent period, which is the time between infection and infectiousness. It is now thought that people can be infectious before showing symptoms, and so the latent period is shorter than the incubation period.
An imported case occurs when a traveler is infected in one area and is reported as sick in another area. Local transmission occurs if that traveler infects others, or if there is a cluster of cases locally and the spread is easily traced. Community transmission occurs when there is no clear source of infection.
Infectivity can be measured using R0. R0 is important epidemiology jargon, short for reproduction number. It is the number of cases, on average, that an infected person will cause during their infectious period. So if R0 =2, then an infected person will infect an average of 2 other people while they are infectious. There are two important variants of the R0. The basic reproduction number represents the maximum potential of a pathogen to infect people – basically what would happen if an infectious person entered a community with no prior immunity. The effective reproductive number describes the current vulnerability of a population based on whether people have immunity thanks to vaccination or prior exposure. The effective R0 decreases over the course of the outbreak. Note that both basic and effective reproduction number depend on factors such as environment and demographics in addition to the pathogen’s infectiousness. The goal of public health interventions is to bring R0 down to less than 1, as this would cause the disease to die out over time.
The seasonal flu has an R0 ranging from 0.9 – 2.1. There is a lot of debate about the R0 of COVID-19, with estimates from more recent data ranging from 2.7-4.2. The variance in these estimates is largely due to differing model assumptions and a lack of data. For example, models which assume the possibility of being infectious before symptom onset have estimates that are around 0.5 higher.
These high R0 estimates mean there is much greater potential for spread of COVID-19 than for the flu. How much greater? For the purpose of this example, let’s say that the flu has an R0 of 1.5 and COVID-19 has an R0 of 3. After three cycles of infection, 11 people have had the flu, and 40 people have been infected with COVID-19. After ten cycles of infection, this becomes 171 people with the flu, and over 88,000 people with COVID-19.
3D Models from:
Global COVID-19 Prevention
This short animated video from Stanford Medicine's Maya Adam illustrates how the novel coronavirus — the virus that causes the respiratory disease COVID-19 — is transmitted among people and how transmission can be prevented.
Get the latest news on COVID-19 testing, treatment, and tracking data:
What Actually Happens If You Get Coronavirus?
What is the coronavirus and what does it actually do in your body?
Mask vs No Mask Lab Results - Do they work?
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