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COVID-19 DIAGNOSIS: MOST ACCURATE TEST? RT-PCR / ANTIBODY DETECTION TEST?

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COVID-19 DIAGNOSIS: MOST ACCURATE TEST? RT-PCR / ANTIBODY DETECTION TEST?

Hi. If you have cough or fever (either low grade or a high grade), with breathing discomfort or any other symptoms, then the only way to find out whether you have COVID-19 or not is to get tested.
In response to the growing COVID-19 pandemic, multiple diagnostic test manufacturers have developed and begun selling rapid and easy-to-use devices.
However, before these tests can be recommended, they must be validated in the appropriate populations and settings. Inadequate tests may miss patients with active infection or falsely categorize patients as having the disease when they do not, further hampering disease control efforts.

Now the question arises, which test to get it done??
Listen to this video till the end to find out about the different kinds of tests available, which diagnostic test is best and how each kind of diagnostic plays a role in the fight against COVID-19.

Disclaimer: Information provided by INTELLECT MEDICOS is not meant to substitute for medical advise by any physician, or experienced health care professional. Always seek advise from your physician about the clinical condition and usage of particular treatment or therapy.

REFERENCES:

1. Liu Y, Liu Y, Diao B, Ren Feifei, et al. Diagnostic indexes of a rapid IgG/IgM combined antibody test for SARS-CoV-2. medxriv [Internet]. 2020;

2. Zhang P, Gao Q, Wang T, Ke Y, et al. Evaluation of recombinant nucleocapsid and spice protein serological diagnosis of novel coronavirus disease 2019 (COVID-19). medxriv [Internet]. 2020;

3. Pan Y, Li X, Yang G, Fan J, et al. Serological immunochromatographic approach in diagnosis with SARS-CoV-2 infected COVID-19 patients. medxriv [Internet]. 2020;

5. Li Z, Yi Y, Luo X, Xion N, et al. Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis. Journal of medical virology.

6. Zhao J, Yuan Q, Wang H, Liu W, Liao X, Su Y, et al. Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. medxriv [Internet]. 2020;

7. Okba N.M.A, Muller M.A., Li W, Wang C, et al. SARS-COV-2 specific antibody responses in COVID-19 patients. medxriv [Internet]. 2020

8. Gorse GJ, Donovan MM, Patel GB. Antibodies to coronaviruses are higher in older compared with younger adults and binding antibodies are more sensitive than neutralizing antibodies identifying coronavirus-associated illnesses. Journal of medical virology.

9. Lin D, Liu L, Zhang M, Hu Y, et al. Evaluation of serological tests in the diagnosis of 2019 novel coronavirus (SARS-CoV-2) infections during the COVID-19 outbreak. medxriv [Internet]. 2020;

10. Wölfel R, Corman V, Guggemos W, Seilmaier M, Mueller M, Niemeyer D, et al. Virological assessment of hospitalized patients with COVID-2019. Nature [Internet]. 2020;

11. Lou B, Li T, Zheng S, Su Y, Li Z, Liu W, et al. Serology characteristics of SARS-CoV-2 infection since the exposure and post symptoms onset. medxriv [Internet]. 2020;

12. Liu W, Liu L, Kou G, Zheng Y, et al. Evaluation of nucleocapsid and spike protein-based ELISAs for detecting antibodies against SARS-CoV-2. medxriv [Internet]. 2020;

13. Zhang W, Du R, Li B, Zheng X, et al. Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes. Emerging microbes and infections. 2020; 9(1):386-389.

14. Zhou P, Yang XL, Wang X, Hu B, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020 Mar;579(7798):270-273. doi: 10.1038/s41586-020-2012-7. Epub 2020 Feb 3.
15. Wang N, Li SY, Yang XL, et al. Serological Evidence of Bat SARS-Related Coronavirus Infection in Humans, China. Virol Sin. 2018;33(1):104–107. doi:10.1007/s12250-018-0012-7

16. Che X, Qiu L, Liao Z, Wang Y, et al. Antigenic cross-reactivity between severe acute respiratory syndrome-associated coronavirus and human coronaviruses 229E and OC43. The Journal of Infectious Diseases, Volume 191, Issue 12, 15 June 2005, Pages 2033–2037,

17.
You can connect with us on:

1. Instagram page: intellect.medicos
(we upload interesting animated mnemonics every day on our page)

2. Facebook page. INTELLECT MEDICOS

#COVID19 #RTPCR #CORONAVIRUS
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Testing for COVID 19 using RT PCR

In this video from our COVID Mini: Diagnostics course, you'll take a deep dive into the RT-PCR process for SARS-CoV-2; learning about how it works, how it can go wrong, and an important value you should look for that may help you predict disease progress.

Continue your understanding of this deadly disease through our COVID Mini: Diagnostics course.

Check out our course library and register for a free trial account:

Please Note: Medmastery's videos, medical lectures, medical illustrations, and medical animations are for medical education and exam preparation purposes, and not intended to replace recommendations by your doctor or health care provider.

#medmastery #coronavirus #COVID19 #sarscov2 #coronaviruschina #coronavirustruth #WHO #wuhan #infection #pandemic #publichealth
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Understanding COVID-19 testing

What is a coronavirus, how many sorts are there and are they all dangerous? Why are there several tests to detect SARS-CoV-2, the virus causing COVID-19? How do the tests work and which one is to be used when?

If you have plenty of questions around COVID-19, if you want to find out what the difference between molecular and antibody testing is, watch this video for answers!

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Roche has been committed to improving lives since the company was founded in 1896 in Basel, Switzerland. Today, Roche creates innovative medicines and diagnostic tests that help millions of patients globally.

Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and neuroscience.

For more information and insights visit:
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Using Reverse Transcription Polymerase Chain Reaction (RT-PCR) in COVID-19 Testing

Testing is key to controlling the spread of the SARS-CoV-2 virus, but how is it done? This animation from Cold Spring Harbor Laboratory’s DNA Learning Center takes an authoritative look “under the hood” of COVID-19 testing. You will learn about a clever method, polymerase chain reaction (PCR), which amplifies the virus genetic “fingerprint” to detect as few as several virus particles present in a throat swab or other patient sample.
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Coronavirus Test: Real time RT-PCR - Animation video

I make animations in biology with PowerPoint, this animation video is about the standard coronavirus test, real time RT-PCR method, which is a laboratory technique combining reverse transcription of RNA into complementary DNA, and amplification of specific DNA targets using polymerase chain reaction (PCR).

Coronavirus Antibody Test - Animation video :


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What Is PCR Testing for COVID-19?

AACC President Dr. Carmen Wiley gives an overview of PCR testing, which is the most common type of test for COVID-19 and the one that patients are currently most likely to encounter.

RT-PCR is the most reliable test in the covid diagnosis: Dr A. Velumani, CEO, Thyrocare Technologies

Testing the accuracy of coronavirus antibody tests

Also known as serological tests, antibody tests can help identify people who have developed an immune response to coronavirus by detecting antibodies in their blood. More than 100 tests have been brought to market since the FDA eased its restrictions to help meet the global demand, but recent data suggests that some of these tests are not as accurate as they should be.

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COVID-19 animation: Coronavirus and antibody testing explained

There are two kinds of tests for viruses like COVID-19. One tests for the presence of the virus in the sample, and the other for antibodies to the virus. Both are important for understanding who is infected and might transmit the virus to others, who have had the virus and might now be immune, and even who might potentially help others with treatment.

The COVID-19 pandemic: testing and PCR diagnostics for COVID

Introduced by virologist and College Fellow, Professor Will Irving, this RCPath seminar series looks at COVID-19 and its implications for and impact on pathology.

The second in our series discusses testing and PCR diagnostics for COVID-19, and is presented by Dr Kate Templeton, Consultant Clinical Scientist in Microbiology at Royal Infirmary, Edinburgh.
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COVID-19 Testing Explained

Curious about COVID-19 testing? Watch Dr. Michael E. Pichichero, an infectious disease specialist and immunologist, and Rebecca Love, a registered nurse and nursing community leader, explain the importance of testing, the various types of tests and how each works, and what’s happening on the front lines during the pandemic.

For more information about COVID-19, please visit the Henry Schein Coronavirus Resource Center at

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Mayo Clinic expert answers questions about antibody testing for COVID-19

A new serology, or antibody, test for COVID-19 has been developed and is now in use by Mayo Clinic Laboratories. . Unlike the molecular diagnostic test for COVID-19, which determines if someone is currently infected with the SARS-CoV-2, the virus that causes COVID-19, serology tests detect a patient's immune response to the virus by specifically looking for antibodies developed against the virus. These antibodies will attach to and essentially kill the virus.

In this Q&A, Dr. Elitza Theel, director of Mayo Clinic’s Infectious Disease Serology Laboratory, answers questions about antibody testing.

Read more:

More health and medical news on the Mayo Clinic News Network.

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What Is The Difference Among RT-PCR, Antibody & Antigen Tests Of Coronavirus? | NewsMo

With India crossing the million mark in Covid cases, there's a need to speed up the testing process. So, what are the required tests? Watch the video to know about different tests done for Coronavirus.
#Newsmo #covid19 #coronavirus #coronavirustesting


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RT-PCR complete (Covid-19). How it works? How Covid-19 test is done?

Most exhaustive information about RT-PCT, types, working principle, requirements, advantages, applications will be coved in this video with a special emphasis on Covid-19 detection.

COVID-19 Molecular Testing

In this month’s “Hot Topic,” Matthew Binnicker, Ph.D., will provide an overview of coronaviruses associated with severe respiratory illness, review the two main laboratory tests, and discuss the factors that influence the sensitivity of PCR for detecting SARS-CoV-2 in patients with COVID-19.
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COVID 19 TESTS | RT-PCR Vs Rapid Antigen Test | कोनसा कोविड टेस्ट करवाए | सबसे अच्छा कोविड टेस्ट

Dr.Maulik Shah describes the basics of all COVID TESTs especially comparing RT-PCR Vs Rapid Antigen Test in the Hindi language.
Disclaimer: This program is meant for general knowledge updating only and not to be taken as medical advice of any form. Consult your doctor for any medical complaints OR Emergency.

#RT-PCR #RapidAntigenTest #COVID19 #Tests

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COVID-19 DIAGNOSIS: MOST ACCURATE TEST? RT-PCR / ANTIBODY DETECTION TEST?

Hi. If you have a cough or fever (either low grade or a high grade), with breathing discomfort or any other symptoms, then the only way to find out whether you have COVID-19 or not is to get tested.
In response to the growing COVID-19 pandemic, multiple diagnostic test manufacturers have developed and begun selling rapid and easy-to-use devices.
However, before these tests can be recommended, they must be validated in the appropriate populations and settings. Inadequate tests may miss patients with active infection or falsely categorize patients as having the disease when they do not, further hampering disease control efforts.

Now the question arises, which test to get it done??
Listen to this video till the end to find out about the different kinds of tests available, which diagnostic test is best, and how each kind of diagnostic plays a role in the fight against COVID-19.

COVID-19 Diagnosis: Rapid Antigen And Antibody Testing | Compare RT- PCR and Rapid Detection.

This video is about COVID-19 diagnosis the Rapid Antigen And Antibody Testing, comparison of RT- PCR and Rapid Detection. This video explains about the Rapid detection test for covid-19 based on antigen detection and based on antibody detection. The mechanism and how these tests are done and what are their present status on the usage for detecting COVID-19. And what is the gold standard testing used in the present to detect COVID-19. The comparison of tests based on the sensitivity and specificity is also explained in this video.
The viewers will get their answer on THE QUESTION AND DOUBTS ABOUT THE MOST ACCURATE TEST? RT-PCR / ANTIBODY DETECTION TEST?
RT PCR test kit how much relaible and sensitive it is in the detection of the COVID-19. Testing Process how it is done Antigen and antibody testing for covid-19. Rapid diagnostic test for covid-19 based on antigen and antibody detection is fully explained.

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Antibody testing for COVID-19 ?

What is the difference between ELISA for antibody testing and PCR for viral detection, what is the clinical significance for each, watch, learn, subscribe and share !

Antibody Testing for COVID-19

Advanced Diagnostic Tools to Optimize Testing for SARS-CoV-2” presented by Dr. Scott Hauenstein, Sr. Scientific Affairs Manager with Bio-Rad Laboratories. Presentation focuses on clinical applications of novel molecular diagnostic tools in human disease. Talk was live August 23rd as a part of the plenary sessions on Antibody Testing for COVID-19, AMLI 2020 (virtual trade show). The following topics are covered: summary of SARS-CoV-2 virology, immunology and the diagnostic tools available to identify and track infections. For more about Bio-Rad's COVID-19 Solutions:

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