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Cure for COVID-19? The drug that has killed Coronavirus in the test tube | 60 Minutes Australia

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Cure for COVID-19? The drug that has killed Coronavirus in the test tube | 60 Minutes Australia

Subscribe here: Full Episodes here | Brave new world (2020)

If there is a glimmer of hope right now its at the University of Queensland’s Centre for Clinical Research. The centre’s director, Professor David Paterson, leads a team that is working on a cure for COVID-19. The key is an existing HIV medication that has shown great promise in the lab.

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For forty years, 60 Minutes have been telling Australians the world’s greatest stories. Tales that changed history, our nation and our lives. Reporters Liz Hayes, Allison Langdon, Tara Brown, Charles Wooley, Liam Bartlett and Sarah Abo look past the headlines because there is always a bigger picture. Sundays are for 60 Minutes.

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Meet the medical detectives tracking the origins of COVID-19 cases | 60 Minutes Australia

Subscribe here: Full Episodes here | On the right track (2020)

When it was confirmed that Channel 9 presenter Richard Wilkins had COVID-19, an incredible mission began, to track down all the people he’d had close contact with and determine if they had been infected too. Medicos, social workers and even military people were tasked with stopping this potential spread of COVID-19. But this wasn’t special treatment just for Wilkins. Liz Hayes reports that there are extraordinary operations like this for every coronavirus case in Australia.

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For forty years, 60 Minutes have been telling Australians the world’s greatest stories. Tales that changed history, our nation and our lives. Reporters Liz Hayes, Allison Langdon, Tara Brown, Charles Wooley, Liam Bartlett and Sarah Abo look past the headlines because there is always a bigger picture. Sundays are for 60 Minutes.

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Whistleblowers silenced by China could have stopped global coronavirus spread | 60 Minutes Australia

Subscribe here: Full Episodes here | Coronavirus crisis: Together, apart (2020)

Mid-November in Wuhan, China, and cases of a strange new flu start surfacing. In a sprawling city of 11 million people, the coronavirus, our invisible brutal enemy was born - festering at least a month and a half before the world was told. In January President Xi Jinping made a decision that would ultimately condemn the world: allowing 5 million people to leave the epicentre of the virus without being screened.

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For forty years, 60 Minutes have been telling Australians the world’s greatest stories. Tales that changed history, our nation and our lives. Reporters Liz Hayes, Allison Langdon, Tara Brown, Charles Wooley, Liam Bartlett and Sarah Abo look past the headlines because there is always a bigger picture. Sundays are for 60 Minutes.

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Scientists look to HIV medications for coronavirus treatment

Scientists working to combat the global coronavirus outbreak are hoping to repurpose drugs used to treat other viruses such as HIV. Over 28,000 cases have been confirmed worldwide, including 12 in the U.S. Dr. David Agus joins CBS This Morning to explain how the drugs may work.

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Each weekday morning, CBS This Morning co-hosts Gayle King, Anthony Mason and Tony Dokoupil deliver two hours of original reporting, breaking news and top-level newsmaker interviews in an engaging and informative format that challenges the norm in network morning news programs. The broadcast has earned a prestigious Peabody Award, a Polk Award, four News & Documentary Emmys, three Daytime Emmys and the 2017 Edward R. Murrow Award for Best Newscast. The broadcast was also honored with an Alfred I. duPont-Columbia Award as part of CBS News division-wide coverage of the shootings at Sandy Hook Elementary School in Newtown, Connecticut. Check local listings for CBS This Morning broadcast times.
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Ivermectin being studied for Coronavirus? | COVID-19

Ivermectin being studied for Coronavirus? | COVID-19
#coronavirus #covid_19 #covid19

Coronavirus (COVID-19) Playlist:

Ivermectin is an FDA approved medication for parasitic infections. Ivermectin is widely available, due to its inclusion on the WHO model list of essential medicines. It opens glutamate-sensitive chloride channel currents in helminths, and it widely believed that this is how it kills certain parasites. Its the drug of choice for the treatment of onchocerciasis and strongyloidiasis. So why might Ivermectin work against SARS-CoV-2?

Once the virus gains entry into the cells of the body, using the ACE2 receptor, the virus releases its messenger RNA into the cell. The cell starts to translate the mRNA from the virus, which starts to make viral proteins, and that’s how new virus forms.

Some of these viral proteins that are freshly made then enter into the nucleus of the cell, or are at least thought to do so by many scientists, and this probably impairs our cells' ability to fight off the infection. The way that these viral proteins are thought to gain entry into the nucleus of our cells is through specific channels that are made out of a different protein, called importin. Not important, importin. There's importin type alpha, importin beta. Or Imp for short, so imp alpha, imp beta.

And this is where ivermectin comes in, because ivermectin inhibits the passage of these viral proteins into the nucleus. It does so by binding to these protein channels and effectively blocking the transport of molecules through them. So this is why scientists started studying ivermectin. And this recent article that just came out April 3rd, in the journal Antiviral Research. This is a pre-proof article, meaning they have been peer-reviewed, but final publication is still pending. What these scientists found is that ivermectin significantly inhibits the SARS-2-CoV viral proteins in their passage from the cytoplasm into the nucleus of cells…... in vitro.

In vitro means, this was done in a test tube, or outside of a living organism.
A single dose of Ivermectin had ∼5000-fold reduction in virus levels at 48h in cell culture. So this drug has a huge impact on this virus in vitro. And that is why the authors of this study conclude that these drugs need to be studied in COVID-19 patients, meaning in clinical trials. The same way that other drugs are being looked at in clinical trials for COVID-19, such as redeliver, chloroquine, and hydroxychloroquine.

So because Ivermectin is generally considered a safe drug and is already FDA approved for other diseases, it can be repurposed for COVID-19, as long as it is shown to be safe and effective for COVID-19 patients in clinical trials.

If this drug turns out to be the miracle drug for Coronavirus, the next question will become, when should people start taking it? Because for the patients with COVID-19 who get very sick, they usually get sick very quickly. So this ivermectin may have to be given prophylactically, or at the first onset of symptoms.

The other question, is what are the side effects, or adverse reactions? Well, base on what we already know about ivermectin, this is what I can tell you.
The most common adverse reaction is the Mazzotti reaction. But this only happens when ivermectin is used to treat onchocerciasis, a parasitic infection. The Mazzotti reaction was first described in 1948. It’s a symptom complex seen in patients after undergoing treatment of nematode infestation, particularly with the medication diethylcarbamazine (DEC), but with ivermectin as well.

Mazzotti reactions can be life-threatening and are characterized by fever, hives, generalized swelling, swollen lymph nodes, fast heart rate, low blood pressure, hypotension, joint pain, and abdominal pain.

There is a 25% chance of Mazzotti reaction when ivermectin is used to treat onchocerciasis, but not other parasitic infections. So if a COVID19 patient took ivermectin, this would not happen.

So, otherwise, Ivermectin is very safe, and side effects are uncommon. Diarrhea occurs in 2% of people taking it.

Also, Ivermectin should not be administered to pregnant or lactating women, and its safety in children less than 15 kg is not known.

Dr. Mike Hansen, MD
Internal Medicine | Pulmonary Disease | Critical Care Medicine
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Coronavirus: Australian scientists may have found cure | Nine News Australia

A head lice treatment could be the cure for the coronavirus as Australian scientists have found a single dose of the drug killed COVID-19 cells in the laboratory. Subscribe: Get more breaking news at:

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Coronavirus global pandemic: a defining moment for the world | 60 Minutes Australia

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When it comes to the coronavirus pandemic, time takes on new meaning. So much is so rapidly changing, it’s overwhelming. But one thing’s certain: right now, Australia is precariously perched on the edge of a frightening medical and economic cliff. While the disease is not being controlled here, COVID-19 is not yet out of control. But as global health experts keep warning us, unless we all drastically change the way we live, we face a bleak future.

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For forty years, 60 Minutes have been telling Australians the world’s greatest stories. Tales that changed history, our nation and our lives. Reporters Liz Hayes, Allison Langdon, Tara Brown, Charles Wooley, Liam Bartlett and Sarah Abo look past the headlines because there is always a bigger picture. Sundays are for 60 Minutes.

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Possible ray of hope for coronavirus treatment l GMA

Health officials are looking into a drug that was developed for Ebola which, could show promise against the coronavirus.

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Medical News | Australian Researcher: Triple Therapy (Ivermectin, Zinc, Doxycycline) for COVID-19

Well-Respected Australian Researcher: Consider Triple Therapy (#Ivermectin, Zinc, #Doxycycline) for COVID-19:
Thomas Borody touts FDA and Australian food and drug authority TGA approved Ivermectin, which he reports to use regularly in his hospital as it evidences positive results for #COVID19 and should be used immediately to fight the pandemic. The developer of the world’s first cure for peptic ulcers, which saved millions of lives worldwide, employed the same methodology to come up with the Ivermectin triple therapy. With over 30 formal clinical trials, many dozens of observational real-world initiatives and hundreds to possibly thousands of doctors already using the medicine, a particular momentum gains speed for additional randomized controlled trials and, just as importantly, a more serious dialogue about the potential of this approach for pragmatic and economical treatment options for COVID-19.


 
TrialSite News Documentary:

TrialSite have produced a documentary on this very topic in South America and will be releasing it to the public by this Friday. In this TrialSite production out of Peru we take an objective probe into the situation in Peru: how did Ivermectin become approved as a drug targeting COVID-19? What data was used as evidence to validate such a decision? Has consensus been met there on the approval or is there debate?


RLF-100 (Aviptadil) Associated with Rapid Respiratory Failure Recovery Among COVID-19 Patients:
Last week we touched on this subject of RLF-100 and this week, we’ll continue to expand on this story. NeuroRX, Inc. and Relief Therapeutics Holdings AG announced that the investigational therapy RLF-100 (Aviptadil) showed evidence of rapid recovery from respiratory failure in the most critically ill patients with COVID-19. In parallel, an independent group of researchers have reported that Aviptadil blocked replication of SARS-CoV-2 in human lung cells and monocytes. The drug has been granted Fast Track designation by FDA and is being developed as a Material Threat Medical Countermeasure in cooperation with the National Institutes of Health and other federal agencies.


Russia’s Gamaleya Vaccine Approved by Russian Health Authorities:
The Russian Health Ministry has approved the world’s first COVID-19 vaccine after fewer than two months of formal human clinical trials. TrialSite News has been following the Gamaleya National Research Institute of Epidemiology and Microbiology (Gamaleya Institute) vaccine effort, and it is suspected that the Russians introduced some form of intensive human challenge trial that started with scientists and perhaps military personnel and then included broader groups, even an elite “VIP” group cohort. Now Russia’s President, Vladimir Putin, proudly declared to all via a televised video conference call with government ministers: “This morning, for the first time in the word, a vaccine against the new coronavirus was registered” in Russia. Putin, in anticipation of the critics, emphatically declared, “I would like to repeat that it has passed all the necessary tests.”


The Need for Convalescent Plasma in TN:
Research is proving convalescent plasma can help those that have COVID-19 recover faster. However, Ballad Health is having to outsource plasma from other regions due to a lack in local donations, but one Northeast Tennessee native is making the most of an unfortunate situation.

UPDATE: Chinese spy spills secrets to expose Communist espionage | 60 Minutes Australia

A self-confessed Chinese spy who bravely outed himself on 60 Minutes has been making headlines around the world ever since. Subscribe here: Full Episodes here

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For forty years, 60 Minutes have been telling Australians the world’s greatest stories. Tales that changed history, our nation and our lives. Reporters Liz Hayes, Allison Langdon, Tara Brown, Charles Wooley, Liam Bartlett and Sarah Abo look past the headlines because there is always a bigger picture. Sundays are for 60 Minutes.

#60MinutesAustralia
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Federal government looks to malaria drug as possible coronavirus treatment

President Trump announced that a drug commonly used to treat malaria could possibly be used to treat coronavirus symptoms, after it goes through clinical trials. However, officials maintained that currently, there is no drug on the market that is FDA-approved to treat coronavirus. Meanwhile in Congress, Senate Majority Leader Mitch McConnell unveiled a financial aid package to help small businesses and industries deeply affected by the coronavirus, like airlines. The proposal has gotten criticism from Democrats, who say it does more to help corporations than workers. Weijia Jiang breaks down what else Washington, D.C. is doing to try and contain the coronavirus' spread.

Coronavirus: radical action needed to stem the spread in Australia | 60 Minutes Australia

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As the coronavirus pandemic escalates in Australia and around the world, 60 Minutes reporter Sarah Abo reports on the latest medical and economic impacts of the crisis.

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For forty years, 60 Minutes have been telling Australians the world’s greatest stories. Tales that changed history, our nation and our lives. Reporters Liz Hayes, Allison Langdon, Tara Brown, Charles Wooley, Liam Bartlett and Sarah Abo look past the headlines because there is always a bigger picture. Sundays are for 60 Minutes.

#60MinutesAustralia

Coronavirus outbreak: Trump says FDA has approved Chloroquine for COVID-19 testing | FULL

U.S. President Donald Trump was joined by VP Mike Pence and other Coronavirus Task Force members to hold a briefing on the efforts taken to develop a COVID-19 treatment on Thursday.

Trump said that Chloroquine, which is a drug used to treat malaria and severe arthritis, has been approved by the Food and Drug Administration (FDA) to be tested as a possible COVID-19 treatment in clinical trials.

At the same briefing, FDA Commissioner Stephen Hahn said he didn't want to provide false hope that chloroquine or other drugs could be an effective treatment.

There are currently no known treatments for the COVID-19 virus and officials have said a vaccine could take up to 12-18 months.

Trump started the briefing by announcing the release of American-Lebanese citizen Amer Fakhoury who has been imprisoned in Lebanon since September 2019.

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Coronavirus medical update: How to treat Covid-19? | COVID-19 Special

As millions of people aroung the globe continue to suffer during the coronavirus pandemic, the entire world is holding out for a cure. The coronavirus pandemic is a test for national governments,the global scientific community and the pharmaceutical industry. The stakes could hardly be higher. How close are we to curing Covid-19?

One drug that's attracted a LOT of attention during the pandemic is Hydroxychloroquin, used to treat malaria. US President Donald Trump claimed he was taking it to help ward off the coronavirus, a course of action scientists do not recommend. That said, there still appears to be some confusion about the drug's effects.

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Gov't recommends use of antiviral drugs for COVID-19 treatment

'고령•중증에 에이즈치료제 권장'…코로나19 치료원칙 나왔다

South Korea has unveiled a set of treatment guidelines for COVID-19.
It consists of administering an anti-HIV medication twice a day.
This is the nation's first treatment protocol for those who show severe symptoms.
Kim Jae-hee has our top story.
Infectious disease experts in South Korea have agreed to the use of antiviral drugs in the treatment of severe coronavirus cases, senior patients, and those with underlying diseases.
On the other hand, it was concluded that young patients, or those with mild symptoms, seemed to have improved after 10 days and without any antiviral treatment.
Young and healthy people have mostly shown improvement without any special treatment. But older patients or those with underlying diseases are in need of the medication from an early stage.
Expert says differences in treatment depending on a patient's age is actually quite normal.
Most viral infections tend to heal even without any treatment... thanks to our body's immune system. But old age in itself can raise risks,... and many senior patients have underlying diseases, so it's recommended that they undergo antiviral treatment.
The government's guidelines recommend Kaletra, an anti-retroviral medication used to treat AIDS for a duration of 7 to 10 days.
Chloroquine or Hydroxychloroquine, a medication used to prevent and treat Malaria can be used as an alternative.
But experts says, while the government's announcement may sound promising, it might not make much of a difference to current treatment methods.
There won't be a significant difference in the treatment methods. It's an antiviral drug that we are already using, and its effectiveness has not been fully proven. It's still just a recommendation.
But the expert is optimistic, saying that the recurrence rate of the novel coronavirus is low.
It seems unlikely that a recovered patient will catch the virus again. In fact, there are very few reports of patients being re-infected when they've recovered from other coronavirus diseases such as SARS and MERS.
He added that all seven of the patients who have made full recoveries in South Korea had no serious underlying diseases, and are unlikely to be re-infected.
Kim Jae-hee, Arirang News.

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Doctor names two drugs that could help treat coronavirus

President Trump expressed optimism on Thursday when he announced that a drug commonly used to treat malaria has been FDA-approved to ease symptoms of the coronavirus. Dr. David Agus joins CBS This Morning to discuss this and other options currently being tried and tested to help battle the illness.

Coronavirus: New drug trial to combat deadly virus | Nine News Australia

Pharmaceutical company Gilead is trialing a drug called remdesivir in China and the US to help those struggling from coronavirus. Subscribe: Get more breaking news at:

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Cure for COVID-19? The drug that has killed Coronavirus in the test tube 60 Minutes Australia

COVID-19 cure news: If there is a glimmer of hope right now its at the University of Queensland’s Centre for Clinical Research. The centre’s director, Professor David Paterson, leads a team that is working on a cure for COVID-19. The key is an existing HIV medication that has shown great promise in the lab.
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COVID-19 nurse explains what's different about treating coronavirus patients | 60 Minutes Australia

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Working alongside Dr Luke Torre in the COVID-19 ward is clinical nurse specialist Linda Cruikshank, who tells reporter Tom Steinfort that treating coronavirus patients is unlike any other due to the isolated nature of the wards and the protective precautions that have to be taken.

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For forty years, 60 Minutes have been telling Australians the world’s greatest stories. Tales that changed history, our nation and our lives. Reporters Liz Hayes, Allison Langdon, Tara Brown, Charles Wooley, Liam Bartlett and Sarah Abo look past the headlines because there is always a bigger picture. Sundays are for 60 Minutes.

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COVID-19 drug breakthrough?

Dr. Simone Wildes discusses a new study from Oxford scientists that shows an inexpensive steroid already on the market may help treat the coronavirus.

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