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DNA Replication | MIT 7.01SC Fundamentals of Biology

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DNA Replication | MIT 7.01SC Fundamentals of Biology

DNA Replication
Instructor: Eric Lander
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DNA Structure and Classic experiments, excerpt 1 | MIT 7.01SC Fundamentals of Biology

DNA Structure and Classic experiments, excerpt 1
Instructor: Eric Lander
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Transcription & Translation | MIT 7.01SC Fundamentals of Biology

Transcription & Translation
Instructor: Sera Thornton
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DNA Structure and Classic experiments, excerpt 2 | MIT 7.01SC Fundamentals of Biology

DNA Structure and Classic experiments, excerpt 2

Instructor: Eric Lander

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Polymerase Chain Reaction (PCR) | MIT 7.01SC Fundamentals of Biology

Polymerase Chain Reaction (PCR)
Instructor: Robert Dorkin
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DNA Structure and Replication: Crash Course Biology #10

Hank introduces us to that wondrous molecule deoxyribonucleic acid - also known as DNA - and explains how it replicates itself in our cells.

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References for this episode can be found in the Google document here:

1:41 link to Biological Molecules

Table of Contents:
1) Nucleic Acids 1:30
2) DNA
-A) Polymers 1:53
-B) Three Ingredients 2:12
-C) Base Pairs 3:45
-D) Base Sequences 4:13
3) Pop Quiz 5:07
4) RNA 5:36
-A) Three Differences from DNA 5:43
5) Biolography 6:16
6) Replication 8:49
-A) Helicase and Unzipping 9:22
-B) Leading Strand 9:38
-C) DNA Polymerase 10:08
-D) RNA Primase 10:24
-E) Lagging Strand 10:46
-F) Okazaki Fragments 11:07
-F) DNA Ligase 11:47

DNA, deoxyribonucleic acid, chromosome, nucleic acid, ribonucleic acid, RNA, polymer, nucleotide, double helix, nucleotide base, base pair, base sequence, friedrich miescher, rosalind franklin, replication, helicase, leading strand, lagging strand, rna primase, dna polymerase, okazaki fragment Support CrashCourse on Subbable:
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DNA replication and RNA transcription and translation | Khan Academy

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DNA Replication - Bruce Alberts (UCSF/Science Magazine)



Dr. Alberts has spent nearly 30 years trying to understand how DNA is replicated. When he began his graduate work in 1961, very little was known about how DNA was copied before each cell division. Alberts describes the key breakthroughs that led to our current understanding of the complex protein machine that drives DNA replication, and he provides some insight on tackling the big problems in biology.

Transcription and Translation, excerpt 1 | MIT 7.01SC Fundamentals of Biology

Transcription and Translation, excerpt 1
Instructor: Eric Lander
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Alternative Approaches to Molecular Biology | MIT 7.01SC Fundamentals of Biology

Alternative Approaches to Molecular Biology
Instructor: Eric Lander
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DNA replication in Prokaryotes 1 | Prokaryotic DNA replication initiation

Prokaryotic DNA replication initiation - This DNA replication lecture explains about the DNA replication process in details. This first lecture of this video series is about the replication initiation in prokaryotes. This lecture explains how the DNA replication initiation take place in E. coli bacteria.
In this Video lecture Prokaryotic DNA replication is explained.
DNA replication will be the procedure for producing 2 equivalent reproductions collected from one of first DNA molecule. This kind of natural method takes place in all residing organisms which is the basis intended for natural monetary gift. DNA comprises of 2 strands in addition to each and every follicle from the first DNA molecule acts being a web template to the manufacturing from the secondary follicle, an operation called semiconservative replication. Cell phone proofreading in addition to error-checking things ensure around great fidelity intended for DNA replication.

In a very mobile, DNA replication commences on unique places, or perhaps sources involving replication, within the genome. Unwinding involving DNA at the origins in addition to activity involving completely new strands brings about replication forks increasing bidirectional through the origins. Many proteins are generally associated with the replication fork which often assists when it comes to the particular initiation in addition to continuation involving DNA activity. Almost all conspicuously, DNA polymerase synthesizes the newest DNA with the addition of secondary nucleotides on the web template follicle.
DNA replication can also be performed throughout vitro (artificially, outside the house the cell). DNA polymerases remote through cells in addition to man-made DNA primers can often initiate DNA activity on regarded sequences in a very web template DNA molecule. The actual polymerase cycle response (PCR), a typical clinical method, cyclically does apply such man-made activity for you to increase a selected goal DNA fragment at a pool area involving DNA.
The particular initiation associated with DNA replication can be mediated by DnaA, the healthy proteins which binds into a region with the foundation known as the actual DnaA package. In Elizabeth. coli, you will discover four DnaA cardboard boxes, every one of which usually boasts a remarkably conserved 9 bp general opinion sequence 5' -- TTATCCACA -- 3'. Joining associated with DnaA to this particular region will cause that being in a wrong way supercoiled. Third ,, a region associated with OriC upstream with the DnaA cardboard boxes (known seeing that DnaB boxes) grow to be melted. There are three of those locations, and every single can be 13 bp prolonged, and AT-rich (which helps shedding since a smaller amount energy is necessary to bust the 2 hydrogen provides which type between A new and Testosterone levels nucleotides). That region gets the general opinion sequence 5' -- GATCTNTTNTTTT -- 3'. Burning with the DnaB cardboard boxes involves ATP (which can be hydrolyzed by DnaA). Subsequent shedding, DnaA utilizes the hexameric helicase (six DnaB proteins) to be able to complete opposite finishes with the melted DNA. This is where the replication derive may type. Recruitment associated with helicase involves six DnaC meats, every one of which can be attached with one subunit associated with helicase. The moment this kind of sophisticated can be created, an extra several DnaA meats emergency for the authentic several DnaA meats in order to create several DnaA dimers. DnaC can be subsequently unveiled, plus the prepriming sophisticated can be finish. In order for DNA replication to continue, SSB healthy proteins is necessary to stop the sole strands associated with DNA from being created almost any second houses and also to reduce them from reannealing, and DNA gyrase is necessary to alleviate the load (by producing damaging supercoils) produced by the actual motion associated with DnaB helicase. The particular relaxing associated with DNA by DnaB helicase makes for primase (DnaG) and RNA polymerase to be able to perfect every single DNA theme to ensure that DNA activity may initiate.
DNA replication by Suman Bhattacharya
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DNA replication in eukaryotes 1 | Introduction

DNA replication in eukaryotes 1 | Introduction - This lecture explains about the DNA replication process in eukaryotes. This lecture introduces the enzymes required for DNA replication.
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Overview of Recombinant DNA, excerpt 1 | MIT 7.01SC Fundamentals of Biology

Overview of Recombinant DNA, excerpt 1
Instructor: Eric Lander
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Constructing and Screening a Recombinant DNA Library | MIT 7.01SC Fundamentals of Biology

Constructing and Screening a Recombinant DNA Library
Instructor: Eric Lander
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Replication and Gene Regulation #1

Bio120 Lecture exploring DNA Replication and Transcription in Bacteria. This lecture was recorded during class.
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DNA Replication Flipped Video Lecture

DNA Replication

Basic Mechanisms of Cloning, excerpt 1 | MIT 7.01SC Fundamentals of Biology

Basic Mechanisms of Cloning, excerpt 1

Instructor: Eric Lander

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DNA replication

DNA replication and its proteins.



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Basic Mechanisms of Cloning, excerpt 2 | MIT 7.01SC Fundamentals of Biology

Basic Mechanisms of Cloning, excerpt 2
Instructor: Eric Lander
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