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Delta Variant Versus Previous COVID 19 Infection vs. Vaccines (Coronavirus Update 128)

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Delta Variant Versus Previous COVID 19 Infection vs. Vaccines (Coronavirus Update 128)

Roger Seheult, MD of MedCram explains how natural immunity (from a previous COVID-19 infection) compares with vaccines (Pfizer, Moderna, AstraZeneca) VS. the Delta coronavirus variant. (This video was recorded on July 24, 2021).

Correction: Strasbourg is in France (near the German border), not in Germany.

TOPICS IN THIS VIDEO INCLUDE:

00:00 Is natural immunity from previous COVID-19 infection strong enough against Delta variant?
00:32 Research study of 50,000+ patients from the Cleveland Clinic
03:07 Qatar airport study shows previous infection with SARS-CoV gives reasonable immunity against reinfection
05:46 UK data suggests low risk of COVID-19 reinfection among population
07:04 Study on antibody response effectiveness (from vaccines and natural infection) at neutralizing several COVID-19 variants, including Delta
13:33 Monoclonal antibodies shown to have little effectiveness against Delta variant
14:31 Patients urged to get both doses of Pfizer or Moderna, especially for protection against Delta variant
14:59 MedCram resources for medical providers treating COVID-19 patients and the case for lung ultrasounds

Roger Seheult, MD is the co-founder and lead professor at
He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

See the video Dr. Seheult references about Lung Ultrasound in COVID 19:

LINKS / REFERENCES:

Can You Get Delta Variant if You Already Had COVID-19? (Healthline) |

Necessity of COVID-19 vaccination in previously infected individuals (medRxiv) |

Associations of Vaccination and of Prior Infection With Positive PCR Test Results for SARS-CoV-2 in Airline Passengers Arriving in Qatar (JAMA) |

New national surveillance of possible COVID-19 reinfection, published by PHE (GOV.UK) |

Study highlights need for full Covid vaccination to protect against Delta variant (STAT) |

All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, delta plus variant COVID, COVID delta variant, and more).


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Video Produced by Kyle Allred


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DISCLAIMER:

MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

#COVID19 #Deltavariant #Coronavirus
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Coronavirus Update 127: Delta Variant and Vaccines

Professor Roger Seheult, MD of MedCram with an update on the effectiveness of four major vaccines against the delta variant of COVID-19: Pfizer / BioNTech, Moderna, AstraZeneca, and Johnson and Johnson Vaccine (This video was recorded on July 19, 2021).

See the video Dr. Seheult references: 10 Tips if you Get COVID-19 here:

Please see our most recent video on Previous Infection vs. The Delta Variant:


TOPICS IN THIS VIDEO INCLUDE:

00:00 General overview of SARS-CoV-2 variants
02:44 Characteristics of the SARS-CoV-2 delta variant (B.1.617.2)
03:21 Preliminary data on delta variant infection rates by age & risk of severe infection
05:14 How delta variant is affecting COVID-19 case numbers in the UK, Israel, and United States
06:55 How do the COVID-19 vaccines stack up against delta variant? Effectiveness of Pfizer-BioNTech vaccine
12:20 Data on the effectiveness of Moderna vaccine against the delta variant
12:42 Data on effectiveness of Oxford-AstraZeneca vaccine against the delta variant
13:41 Information on Johnson & Johnson vaccine effectiveness against related SARS-CoV-2 variants (no current data on delta variant)
15:29 Vaccination rates across the United States
17:04 What to do if you’re infected with COVID-19?


Roger Seheult, MD is the co-founder and lead professor at
He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.


LINKS / REFERENCES:

5 Things To Know About the Delta Variant (Yale Medicine) |

REACT-1 round 12 report: resurgence of SARS-CoV-2 infections in England associated with increased frequency of the Delta variant (Imperial College) |

SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness (The Lancet) |

Vaccines highly effective against B.1.617.2 variant after 2 doses (GOV.UK) |

Effectiveness of COVID-19 vaccines against hospital admission with the Delta (B.1.617.2) variant (Public Health England) |

Moderna Provides a Clinical Update on the Neutralizing Activity of its COVID-19 Vaccine on Emerging Variants Including the Delta Variant First Identified in India (Moderna) |

How much protection COVID-19 vaccines give you against the Delta variant, according to the best available data (Business Insider) |

The total number and mass of SARS-CoV-2 virions (NIH) |

Covid vaccine: How many people in the UK have been vaccinated so far? (BBC News) |

All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, delta plus variant COVID, COVID delta variant, and more).


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DISCLAIMER:

MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

#COVID19 #SARSCoV2 #Coronavirus
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COVID-19: Variants and Vaccines

Dr. Gregory Poland discusses the latest information on SARS-CoV-2 viral variants, and COVID-19 vaccine efficacy. He also speaks about a framework within which to think about and educate on COVID-19 vaccine reactogenicity and safety.
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The Delta Variant and Vaccine Protection

What's the deal with Covid variants? How well do the different Covid vaccines protect against the several variants? Today we'll tell you about the several variants, including the Delta variant that is prevalent in the US, and we'll talk about the studies that have looked at vaccine efficacy against these variants.

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#healthcaretriage #covid #deltavariant
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The Delta Variant: Current Evidence and Literature - COVID-19 | SARS-CoV-2 | Vaccine Efficacy

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In this lecture Professor Zach Murphy will be presenting on The Delta Variant: Current Evidence and Literature - COVID-19 | SARS-CoV-2 | Vaccine Efficacy- as of August 16, 2021.

During this lecture we will be providing you with the most up to date evidence and literature discussing the Delta Variant and current state of the COVID-19 pandemic. We will begin this lecture by referring to the whiteboard on the current variants of concern and their pathophysiology. Next, we will take a look at current research supporting variants of concern and their relevant attributes. We will then be discussing the research defining the viral load of the Delta variant, and will then support this with evidence from a variety of reputable sources including UpToDate and the CDC. The next chapter of this lecture is a brief discussion on the overall transmissibility of the Delta variant. We look at the transmissibility or the spreadability of this Delta variant in comparison to ancestral strains and the Alpha variant. We will support these findings with current evidence on transmissibility from Public Health England and the CDC. Following this discussion, we move into the severity of the Delta variant in comparison to ancestral strains and the Alpha variant. Once again, we utilize the whiteboard and recently published articles to support our findings on the severity of the Delta variant. We will then transition into the prevalence / most affected populations in regard to the Delta variant. We support our lecture through the use of articles / research studies published by Public Health England, CDC, and The New York Times. The next chapter of our lecture is a discussion on the symptoms and treatment of COVID-19, particularly those affected by the Delta variant. We highlight the different symptoms patients are presenting with in comparison to ancestral strains and the Alpha variant. Finally, we conclude this lecture with a very important discussion on vaccine efficacy, and the potential risk of reinfection rates in regard to the Delta variant. We hope you enjoy this lecture and be sure to support us below!

References:

Table of Contents:
0:00 Lab
0:08 The Delta Variant Introduction
0:40 Variants of Concern / Pathophysiology
8:42 Viral Load
10:44 Transmissibility
14:27 Severity
18:55 Prevalence / Populations Affected
28:32 Symptoms associated with Delta Variant
33:04 Treatment of COVID-19
45:43 Vaccine Efficacy | Pfizer/BioNTech + Moderna + AstraZeneca
1:01:14 Prevention, Masks, NPI
1:04:20 Reinfection Rates
1:10:09 Comment, Like, SUBSCRIBE!

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COVID Variants vs. Coronavirus Vaccines (AstraZeneca, Pfizer, Moderna, Johnson & Johnson) + Immunity

Renowned virologist Shane Crotty, PhD joins us again to address the most important COVID-19 questions: Should people who’ve been vaccinated or had COVID-19 continue to wear masks and physically distance? How will each vaccine hold up to the SARS-CoV-2 variants? What does the research say about people who’ve already had COVID-19 who get a vaccine? How long will immunity last for the vaccines or COVID-19 infection?

Shane Crotty is a Professor at the La Jolla Institute for Immunology, Center for Infectious Disease and Vaccine Research, Crotty Lab. Prof. Crotty also has an academic appointment with the University of California San Diago. See his full bio here:
Prof. Crotty on Twitter:

Interviewer: Kyle Allred, Physician Assistant, Producer and Co-Founder of MedCram.com

(This video was recorded on March 23, 2021)

Just to clarify at 8:40 in the video: Prof. Crotty is describing a theoretical person when he says I myself am comfortable getting infected... He hasn't had COVID, and doesn't have that opinion. He was explaining one end of the spectrum of level of concern for individuals.

TOPICS DISCUSSED IN THIS VIDEO INCLUDE:

0:00 Intro
0:46 Heated exchange between Dr. Fauci and Senator Rand Paul
1:00 How long does immunity last for those who’ve had COVID-19?
3:31 How antibody levels and T cells drop over time
4:03 Dr. Fauci: Difference between in vitro and real-world studies
4:36 Population-based studies about COVID 19 immunity against reinfection
6:22 Huge variability from person to person for post coronavirus immunity
8:20 Policy decision: individual vs. community goals during a pandemic
9:03 Very rare for hospitalization from COVID-19 reinfection
9:34 Avoiding COVID-19 infection and transmission potential
10:12 Should mask-wearing continue for those who’ve had COVID-19?
12:23 If I’ve had COVID-19, shouldn’t my vaccine dose go to someone else?
13:39 Vaccines are eliciting more immunity than natural infection
14:02 Is natural immunity always better than a vaccine?
20:05 If you’ve had COVID-19, when should you get vaccinated? Both doses?
22:07 How are variants “game changers” for vaccines and natural infections?
24:53 Can’t I stop wearing masks and distancing after a vaccine or having COVID?
26:14 Variants of concern: B.1.1.7 (UK) and B.1.351 (S. Africa) details and implications
30:57 South Africa Variant escaping immunity: AstraZeneca Vaccine data
32:28 Isn't preventing COVID 19 hospitalizations and deaths the primary goal?
35:25 Will we need updated coronavirus vaccines?
36:38 Johnson and Johnson vaccine versus the variants
37:57 Preventing transmission to prevent SARS CoV 2 mutation opportunities
38:40 Coronavirus antibodies vs T Cells and other parts of the immune system
39:54 Replication and asymptomatic spread of COVID-19 vs. Pneumonia
42:53 Vaccine incentives and Senator Rand Paul's perspective
45:35 Looking ahead, SARS-CoV-2 vs Influenza, Will we need annual vaccinations?
52:20 Current research and goals for Prof. Shane Crotty

PREVIOUS MEDCRAM DISCUSSIONS WITH PROF. CROTTY :
(Dec 16, 2020)
(January 5, 2021)

REFERENCES:

Crotty's Research Published in Science |

Variant Tracker |

Denmark Research in the Lancet |

UK SIREN study:

Research from Qatar |

UK Research in NEJM |

Qatar:

Congressional Hearing 3/8/21: exchange with Dr. Fauci and Rand Paul: (PBS News Hour) and (CNBC)


THE MEDCRAM WEBSITE:

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All coronavirus updates are at MedCram.com ad-free (including more on RNA vaccines, COVID variants, South African Variant, Johnson and Johnson vaccine for COVID 19, and more):


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MEDIA CONTACT:

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Video Produced by Kyle Allred


DISCLAIMER:

MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
#COVID19 #Coronavirus #COVID19UK

COVID-19 Delta Variant - Masks for Fully Vaccinated People Explained

Dr. Stuart Cohen, Director of Hospital Epidemiology and Infection Control at UC Davis Medical Center, explains why the COVID-19 Delta variant is more easily transmitted than previous variants, how masks should still play a role in keeping you safe (even if you are vaccinated) and why getting a COVID-19 vaccine is vital for preventing future variants of the novel coronavirus.

Learn more about Delta and masking:
For the latest information and resources on COVID-19, visit
See the latest news from UC Davis Health:

#covid19 #deltavariant #coronavirus #delta #ucdavis

Delta Variant: Top 10 COVID Questions and How to Prepare

A coronavirus (COVID-19) variant has become dominant in the USA and Roger Seheult, MD of MedCram responds to 10 common questions including:

00:00 If someone is fully vaccinated or already had COVID, how worried should they be about the Delta Variant?
02:16 Should we be getting booster COVID vaccine doses?
05:36 Will there continue to be more variants, perhaps even variants more challenging that the Delta variant?
07:24 Is Long COVID occurring in the fully vaccinated?
08:26 When is this surge going to peak? Can we learn from other countries?
12:52 Are more children getting hospitalized with COVID 19 Delta variant?
14:03 What happens when school starts?
16:06 Have treatment and testing strategies changed for Delta variant?
19:45 What can we do to protect ourselves and our communities from the coronavirus Delta variant and future COVID mutations?

This video was recorded on August 6, 2021

Roger Seheult, MD is the co-founder and lead professor at
He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.

Interviewer: Kyle Allred, Physician Assistant, Producer, and Co-Founder of MedCram.com

LINKS / REFERENCES:

COVID-19 Ventilator Course:

Lung Ultrasound in COVID 19:

Delta Variant vs. Previous COVID-19 Infection | MedCram:

Delta Variant vs. Vaccines | MedCram:

10 Tips If You Get COVID-19 | MedCram:

Worldometer:

Covid-19 Breakthrough Infections in Vaccinated Health Care Workers
List of authors | NEJM:



WHO calls for halting COVID-19 vaccine boosters in favor of unvaccinated |

AMA Physicians Survey |

Covid-19 Breakthrough Infections in Vaccinated Health Care Workers | NEJM:

Six Month Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine | MedRxiv:

The key numbers from the CDC’s new assessment of the delta variant | WP:

All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, delta plus variant COVID, COVID delta variant, and more).


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MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested.


MEDIA CONTACT:

Media Contact: customers@medcram.com
Media contact info:

Video Produced by Kyle Allred


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DISCLAIMER:

MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.

#COVID19 #Deltavariant #Coronavirus

Fact check: Do COVID-19 vaccines protect against the delta variant? | DW News

Worldwide, some people died of the delta variant despite being fully vaccinated. Is the COVID-19 vaccination no longer sufficient? A look at the facts shows: Yes, complete vaccinations are still the best protection you can get against delta.

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Pfizer developing Covid-19 vaccine booster targeting Delta variant

CNBC's Meg Tirrell reports on Pfizer's update regarding its Covid-19 booster shot.
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The COVID-19 Delta Variant Explained

Dr. Lorena Garcia, professor of epidemiology at UC Davis School of Medicine, explains how the COVID-19 Delta variant is different, what you can do to stay safe and how vaccines could make a difference in preventing future COVID-19 variants.

Learn more about the Delta variant:
For the latest information and resources on COVID-19, visit
See the latest news from UC Davis Health:

0:00 What should we know about the COVID-19 Delta variant?
0:57 How does the Delta variant compare to other COVID-19 variants?
1:58 How do vaccines affect COVID-19 variants?

#delta #deltavariant #covid19 #coronavirus #ucdavis

Delta Covid variant In Israel Infects Some Fully Vaccinated Adults

Israel began relaxing its Covid-19 restrictions after a widely successful vaccine rollout, but some fully vaccinated adults have caught the virus, raising concerns that the delta variant is spreading through the country. NBC News’ Raf Sanchez is in Tel Aviv to explain how Israel is trying to contain variant outbreaks.  

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The Delta Variant, Vaccine Effectiveness and Development of Intranasal COVID-19 Vaccines

How dangerous is the Delta variant? Do vaccines remain protective against Delta? Why are fully vaccinated people still transmitting the virus? What can be done to slow viral evolution?

In this race for survival of the fittest, Delta, which the World Health Organization has called the “fastest and fittest variant so far,” has given the virus an edge. Thanks to a series of mutations in the spike protein, the portion of the virus that binds to human ACE2 receptors and mediates viral entry, Delta is 40-60% more transmissible than Alpha and almost twice as transmissible as the original Wuhan strain.

The key is to get ahead of the natural selection that’s occurring. If we want to stop SARS-CoV-2 from continuing to evolve and spread, we need to simultaneously reduce case numbers and increase immunity.

Takeaways from today’s session about the SARS-CoV-2 Delta variant, vaccines and mucosal immunity:

- The Delta variant is 40-60% more transmissible than Alpha and almost twice as transmissible as the original Wuhan strain.

- Vaccines remain highly effective at preventing hospitalization and death from Delta infection.
Data indicate that vaccinated individuals may still be able to transmit the virus.

- This is due, in part, to the generation of insufficient mucosal immunity via systemic injection to remain protective long term.

- Mucosal routes of immunization are under investigation, with a number of intranasal vaccines entering clinical trial.

In combination, vaccination and masking can reduce the risk of severe disease, slow transmission and reduce the evolution of SARS-CoV-2.

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Delta Plus Variant Likely To Defeat Vaccines And Infection Immunity? Experts Believe So

But now there is a growing concern about its most recent mutation known as Delta Plus or AY.01. Reports suggest the Delta Plus variant could evade both vaccine and infection immunity. Meanwhile, the Union health ministry has still not classified the Delta plus variant as a ‘variant of concern’
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Should Vaccinated People Be Concerned About The Delta Variant?

NBC News medical contributor Dr. Kavita Patel explains whether vaccinated people should resume wearing masks as the delta variant intensifies its spread across the U.S.» Subscribe to NBC News:
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Should Vaccinated People Be Concerned About The Delta Variant?
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COVID-19 Delta Variant Survivor Grateful for Vaccine

A COVID-19 delta variant survivor hopes his personal experience will convince others to roll up their sleeve and get vaccinated. Ginger Conejero Saab reports.

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The Coronavirus Pandemic: The Delta Variant Surge

The highly infectious COVID-19 Delta variant is spurring global surges, sparking concerns among public health officials. In the U.S., more than 80 percent of new cases are from the Delta variant. What makes this variant so contagious? How protective are current vaccines? What’s the latest on practices such as masking and social distancing? Join Harvard Chan epidemiologist William Hanage and The World’s Carolyn Beeler for this online Q&A.

Presented jointly with The World from PRX & GBH.

Covid-19: Can vaccines keep up with variants? | The Economist

The race between covid-19 vaccines and variants is on. Alok Jha, The Economist’s science correspondent, and Natasha Loder, health policy editor, discuss what this means for the future

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Mayo Clinic Q&A podcast: The COVID-19 delta variant has changed everything

A fourth COVID-19 surge is blanketing the U.S. and the delta variant is the culprit.

Where did this delta variant come from? It came from unvaccinated people getting infected in large numbers allowing the virus to continue mutating, says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.

In the past, a person with COVID-19 might infect two to four people. But with the delta variant, one person can infect nine people, according to Dr. Poland. He says if you want to protect yourself, and your family, wear a mask, especially indoors, and get vaccinated with an appropriate series of one of the COVID-19 vaccines.

These are the most studied vaccines in the history of the world, Dr. Poland emphasizes. There have never been this many people, who have received this many doses of vaccines, during this amount of time, with as much scrutiny as these COVID-19 vaccines have had.

In this Mayo Clinic Q&A podcast, Dr. Poland answers questions about a person's waning immunity and the likelihood of COVID-19 booster shots. He also explains the two phases of immunity and goes into detail about the extensive FDA license approval process for the vaccines.

___________________________________________

Information in this post was accurate at the time of its posting. Due to the fluid nature of the COVID-19 pandemic, scientific understanding, along with guidelines and recommendations, may have changed since the original publication date.

For the safety of its patients, staff and visitors, Mayo Clinic has strict masking policies in place. Anyone shown without a mask was recorded prior to COVID-19 or recorded in an area not designated for patient care, where social distancing and other safety protocols were followed.

Dr. Poland has served as a consultant for Merck & Co. Inc., Medicago Inc., GlaxoSmithKline plc, Sanofi Pasteur, Emergent BioSolutions Inc., Dynavax Technologies Corp., Genentech Inc., Eli Lilly and Co., Janssen Pharmaceuticals Inc., Kentucky BioProcessing Inc. and Genevant Sciences Corp. Honoraria: Elsevier.

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How effective are COVID-19 vaccines against variants?

Dr. Darien Sutton shares some encouraging news about the Pfizer and Moderna vaccines’ efficacy against the delta variant.

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