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Hack your DNA with CRISPR - VPRO documentary - 2018

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Hack your DNA with CRISPR - VPRO documentary - 2018

You won't be able to blame it on your genetics anymore: with CRISPR, it's so easy to hacn into your DNA. CRISPR technology is our future, and experiments with DNA hacking are booming. CRISPR biotechnology is not science fiction anymore, it is our very near future. Would you hack and reprogram your own DNA with CRISPR? Breaking the code of life, hacking DNA at home.

Welcome to the world of a new nature. We can now literally cut and paste DNA with the new CRISPR technology. There is a revolutionary development going on that will have major consequences for humans, plants and animals. The new biotechnology is here.

'Bio is the New Digital'. We are able to accurately reprogram the genetic code of our body cells, embryos, bacteria, viruses and plants. With the CRISPR technology we can adjust the characteristics of each organism to our needs. This allows us to permanently ban diseases, improve our body conditions and adapt plants to our food needs.

The special feature of CRISPR technology is that it is relatively simple. In the past year, the number of experiments and applications has exploded. Around the world, people have been tinkering with CRISPR: experimenting at home with the 'Do it Yourself CRISPR kits'.

Scientists call for new ethical frameworks. The demand for the (un)desirable so-called designer babies is imminent. Although this is not yet the case, we can put an end to hereditary diseases in the short term. We may also want to make bacteria that can eat oil or plastic, pigs in which human organs can grow or bring extinct animals back to life.
It looks like science fiction but it is now closer to our reality than ever.
With: Emmanuelle Charpentier (geneticist), John van der Oost (microbiologist), Andrew Hessel (biotechnologist), Niels Geijsen (cell biologist), Josiah Zayner (biohacker) and Ivan van der Meij (FSHD patient).

Originally broadcasted by VPRO in 2018.
© VPRO Backlight Mars 2018

On VPRO broadcast you will find nonfiction videos with English subtitles, French subtitles and Spanish subtitles, such as documentaries, short interviews and documentary series.
VPRO Documentary publishes one new subtitled documentary about current affairs, finance, sustainability, climate change or politics every week. We research subjects like politics, world economy, society and science with experts and try to grasp the essence of prominent trends and developments.

Subscribe to our channel for great, subtitled, recent documentaries.

Visit additional youtube channels bij VPRO broadcast:
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Credits:
Director: Rob van Hattum
Research: William de Bruijn
English, French and Spanish subtitles: Ericsson.
French and Spanish subtitles are co-funded by European Union.
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Meet the biohacker using CRISPR to teach everyone gene editing

Meet the biohacker who wants to teach everyone how to edit genes

Josiah Zayner is a biohacker who thinks everyone should be able to change their DNA with biotechnology called CRISPR. That’s why he founded a company called The ODIN, which sells do-it-yourself biotech kits that teach people how to genetically modify bacteria and frogs. It's DIY gene therapy.

His company has sold tens of thousands of experiments using CRISPR, an inexpensive and precise gene-editing technology that has revolutionized the field.

Find more on CRISPR at Quartz

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CRISPR in Context: The New World of Human Genetic Engineering

It’s happened. The first children genetically engineered with the powerful DNA-editing tool called CRISPR-Cas9 have been born to a woman in China. Their altered genes will be passed to their children, and their children’s children. Join CRISPR’s co-discoverer, microbiologist Jennifer Doudna, as we explore the perils and the promise of this powerful technology. It is not the first time human ingenuity has created something capable of doing us great good and great harm. Are we up to the challenge of guiding how CRISPR will shape the future?

PARTICIPANTS: Jennifer Doudna, Jamie Metzl, William Hurlbut

MODERATOR: Guy McKhann

MORE INFO ABOUT THE PROGRAM AND
PARTICIPANTS:

TOPICS
0:00 - Introduction
1:55 - Jennifer Doudna introduction
2:25 - How do we learn to use CRISPR technology wisely?
3:29 - The basics of understanding CRISPR
6:04 - Genetic engineering explainer film
7:39 - How can CRISPR help the worldwide food chain?
9:57 - Genetic disease treatment
14:25 - Improving quality of life
15:55 - Designer babies
17:55 - The gene drive
19:25 - Confronting the ethical implications of CRISPR
23:55 - Jennifer’s childhood in Hawaii
28:25 - Patents
32:08 - Importance of accuracy
32:40 - Germ cells vs somatic cells
35:58 - He Jiankui controversy
40:05 - What makes CRISPR dangerous?
43:48 - How do we enforce regulation of CRISPR use?
53:50 - The aftermath of He Jiankui’s work
1:09:25 - How do we make CRISPR technology accessible globally?
1:14:00 - How do we balance natural biology and CRISPR?
1:18:44 - How will CRISPR impact our future as a species?

PROGRAM CREDITS
- Produced by Nils Kongshaug
- Associate Produced by Emmalina Glinskis
- Music provided by APM
- Additional images and footage provided by: Getty Images, Shutterstock, Videoblocks.
- Recorded at the Simons Foundation's Gerald D. Fishbaum Auditorium

The Kavli Prize recognizes scientists for their seminal advances in astrophysics, nanoscience, and neuroscience. The series, “The Big, the Small, and the Complex,” is sponsored by The Kavli Foundation.

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The Realities of Gene Editing with CRISPR I NOVA I PBS

CRISPR gene-editing technology is advancing quickly. What can it do now—and in the future?

The revolutionary gene-editing tool known as CRISPR can alter, add, and remove genes from the human genome. The implications are immense: It could help eliminate illnesses like sickle cell disease and muscular dystrophy, and could even allow us to alter the genes of future generations of humans, leading to so-called designer babies. But will this ever really happen?

Medical journalist and pediatrician Alok Patel investigates the current state of CRISPR—starting with a bull calf named Cosmo. Patel discovers how scientists edited Cosmo’s genome so he would produce more male offspring, and what that means for humans. In conversation with scientists, artists, and ethicists, Patel explores what kind of gene editing is actually possible right now—and what we should be thinking about when we consider manipulating human traits and, ultimately, the human experience.

PRODUCTION CREDITS:

Hosted by Dr. Alok Patel

WRITTEN, PRODUCED AND DIRECTED BY
Caitlin Saks

EDITED BY
Robert Kirwan

ASSISTANT EDITOR
Jay Colamaria

CAMERA
Arlo Pérez

UC DAVIS FIELD DIRECTOR / CAMERA
Zachary Fink

ASSOCIATE PRODUCERS
Ana Aceves
Christina Monnen
Arlo Pérez
Jay Colamaria

PRODUCTION ASSISTANT
Lorena Lyon

INTERNS
Jessie Hendricks
Samuel Lipsey

AMERICAN SIGN LANGUAGE / ENGLISH INTERPRETER
Adam Bartley

ANIMATION
Edgeworx Studios

ADDITIONAL ANIMATION
2K-12 Studios
Mitch Butler

MUSIC
APM

ONLINE EDITOR AND COLORIST
David Bigelow

AUDIO MIX
Chris Anderson

ARCHIVAL MATERIAL
AP Archive
Broad Institute of MIT and Harvard
Getty Images
He Jiankui Lab / CC BY
Penn Medicine
Pond 5
Storyblocks

SPECIAL THANKS
Mike Baylis -- Assisted in the set up of a remote interview, at no cost.
Isaac Plant -- Reviewed script and graphics for scientific accuracy, at no cost.
Elizabeth Delgado -- Reviewed script and graphics for scientific accuracy, at no cost.
Dr. Samira Kiani -- Reviewed script and graphics for scientific accuracy, at no cost.
Dr. Kim Thornton -- Interviewed but did not include in the final film, at no cost.

Participants:
Françoise Baylis
Teresa Blankmeyer Burke
Karmella Haynes
Xavier LaPlante
David Liu
Bret McNabb
Liana Novoa
Alok Patel
Ariana Pelaez
Brianna Sapienza
Niaz Uddin
Alison Van Eenennaam

Image credit: (DNA helix)

© WGBH Educational Foundation
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Unnatural Selection: Season 1 | Main Trailer | Netflix

The documentary series UNNATURAL SELECTION explores new developments in the science of gene-editing that defy evolution and raise moral, social and environmental impact questions about where we, as a society, draw the line.

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Splicing and Dicing DNA: Genome Engineering and the CRISPR Revolution

CRISPR: It’s the powerful gene editing technology transforming biomedical research. Fast, cheap and easy to use, it allows scientists to rewrite the DNA in just about any organism—including humans—with tests on human embryos already underway. The technique’s potential to radically reshape everything from disease prevention to the future of human evolution has driven explosive progress and heated debate. Join the world’s CRISPR pioneers to learn about the enormous possibilities and ethical challenges as we stand on the threshold of a brave new world of manipulating life’s fundamental code.

This program is part of the Big Ideas Series, made possible with support from the John Templeton Foundation.

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Original Program Date: June 3 2016
MODERATOR: Richard Besser
PARTICIPANTS: George Church, Luke Dow, Josephine Johnston, Ben Matthews, Harry Ostrer, Noel Sauer

What is CRISPR? 00:05

Introduction by Richard Besser 3:58

Participant Introductions. 5:02

What is so powerful about CRISPR? 7:25

How is CRISPR is used? 13:00

How will CRISPR help eliminate Zika Virus? 20:45

Modifying 60 genes at once in a pig. 26:02

What are potential agricultural advantages from CRISPR? 28:44

If you have eaten CRISPR cells? 35:00

Using a gene drives to eliminate virus? 37:40

Creating an off switch for CRISPR 40:27

How is it ethical to not rid the world of malaria? 42:55

What is the difference between editing a germ line and editing a cancer cell? 48:27

Why would the first CRISPR baby create backlash? 58:48

How do we regular CRISPR used in military applications? 1:06:33

What is the regulation to be expected from CRISPR? 1:13:09

What does a CRISPR-ised world look like? 1:16:00

Wie wir unsere DNA mit der CRISPR-Methode hacken können - 2018

Man wird es nicht mehr so einfach auf die Genetik abwälzen können, denn mit der CRISPR-Methode können wir unsere eigene DNA hacken. Die CRISPR-Technologie ist die Zukunft, und Experimente mit DNA-Hacking boomen. CRISPR-Biotechnologie ist keine Science-Fiction, sondern Realität. Würden Sie Ihre eigene DNA mit CRISPR hacken und neu programmieren? Den Lebenscode Zuhause hacken und ihn neu programmieren, warum nicht?

Willkommen in der schönen neuen Welt, wo wir buchstäblich an unserer DNA herumschnipseln und mit der neuen CRISPR-Technologie so zusammenfügen, wie wir wollen. Eine revolutionäre Entwicklung, die für Menschen, Pflanzen und Tiere langfristig Konsequenzen haben wird. Eine neue Biotechnologie, die unser Leben verändert. Wir sind in der Lage, den genetischen Code unserer Körperzellen, Embryonen, Bakterien, Viren und Pflanzen neu zu programmieren. Mit der CRISPR-Technologie können wir die Eigenschaften jedes Organismus an unsere Bedürfnisse anpassen. Dies ermöglicht uns, Krankheiten auszumerzen und unsere Körperbedürfnisse und Bedürfnisse zu verbessern.

Das Besondere an der CRISPR-Technologie ist, dass sie relativ einfach ist. Im vergangenen Jahr ist die Anzahl der Experimente explodiert. Auf der ganzen Welt basteln Menschen an ihrer eigenen DNA herum. Sie experimentieren zu Hause mit den „Do it Yourself CRISPR-Kits“.

Wissenschaftler fordern neue ethische Rahmenbedingungen. Die Nachfrage nach den (un-) erwünschten sogenannten Designer-Babys steht unmittelbar bevor. Obwohl dies noch nicht der Fall ist, können wir Erbkrankheiten kurzfristig ein Ende bereiten. Wir können auch Plastik- oder Plastikschweine herstellen, in denen menschliche Organe wachsen oder Tiere zurück ins Leben bringen können. Was wie ein Science-Fiction-Film daherkommt, kann schon bald unsere Realität werden.

Mit Emmanuelle Charpentier (Genetiker), John van der Oost (Mikrobiologe), Andrew Hessel (Biotechnologe), Niels Geijsen (Zellbiologe), Josiah Zayner (biohacker) und Ivan van der Meij (FSHD Patient).
© Ursprünglich ausgestrahlt von VPRO im März 2018

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Crispr Cas9 & Fluorescent Yeast: Genetic Engineering at Home

Genetic engineering with Crispr Cas9 - no longer confined to the lab!

This video demonstrates the 'Bacterial CRISPR and Fluorescent Yeast Combo kit' from the company The Odin. The Yeast is engineered using a plasmid, so you get to see a more conventional method along with Crispr Cas9.

Special Thanks to Dr. Karen Maxwell.

Link to the kit from The Odin:


What is CRISPR? (video by Bozeman Science)


Genome Editing with CRISPR-Cas9 (video by McGovern Institute for Brain Research at MIT)


More Crispr Cas9 Info:



More info on Plasmids:



Music:
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Into the Future with CRISPR Technology with Jennifer Doudna

(4:54 - Main Presentation, 54:36 - Q&A)
Jennifer Doudna, co-discoverer of CRISPR-Cas9, discusses how genome editing with CRISPR technology is transforming biology. CRISPR-Cas9, an RNA-guided enzyme with remarkable abilities to recognize and cleave DNA, operates by mechanisms that both explain its biological function and provide insights into technology development. Doudna covers research into this amazing family of proteins: where they came from, how they work and how CAS-9-based technologies are revolutionizing research, biomedicine and agriculture. Recorded on 10/07/2019. [11/2019] [Show ID: 35215]

UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world.
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DIY Biohackers Are Editing Genes in Garages and Kitchens

With the latest breakthroughs in the life sciences, who needs a lab or degree?
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A biohacker for me is somebody who is doing something clever or interesting in biology, says Josiah Zayner, a molecular biophysicist who runs The ODIN, a company that sells do-it-yourself genetic engineering kits. They're usually these people that have been fucked by the system who are trying to unfuck themselves.

Zayner is one of the leading figures in the biohacking movement and is the main organizer of the BioHack the Planet Conference, a yearly gathering of citizen scientists. This year, over 100 members of the biohacking community met in Oakland, California to discuss a wide array of issues from at-home genetic engineering to questions on bioethics.

Biohackers have often been compared to computer hackers of the 1980s, but instead of breaking into and manipulating information technology systems, they're focused on hacking living organisms with the hopes of curing illnesses and in some cases obtaining superhuman powers.

Their shared mission is to put this technology into the hands of as many people as possible.

People should be able to use all the technologies that science develops, says Zayner. It shouldn't just be patented and given to companies or exclusively given to certain people.

These do-it-yourself biologists say the democratization of science has given them the freedom to do work on projects that are often ignored by larger institutions. They're using gene editing technologies like CRISPR to create personalized treatments for those suffering from rare diseases or cancer, reverse engineering pharmaceuticals like Epi-Pens so people can make their own medicine at home, and even creating glow in the dark beer.

I think this is the most exciting time thus far in the history of the world to be alive with respect to what we can and will do with life forms, says Hank Greely, the director of the Center for Law and the Biosciences at Stanford University.

But breakthroughs in the world of biohacking are drawing more scrutiny from federal regulators. Earlier this year, the Food and Drug Administration began placing restrictions on non-human genetic modifications and declared that genetically edited animals must be classified as drugs. This gives the agency broad authority over a number of do-it-yourself genetics tests and requires experiments involving animals to go through the same vetting process as a new drug.

I guess they couldn't call them cosmetics and they couldn't call them foods, so they're like dogs are drugs, states David Ishee, a Mississippi canine breeder who is working on editing out genetic diseases in dogs. Everybody's worried about what someone could do with this technology and nobody seems to care about the damage that not doing it will cause because these animals are dying.

Increasing regulation could undermine biohacking breakthroughs for humans as well.

I'm a huge fan of deregulation because I believe in the inherent goodness of capitalism, says Zayner. Stuff doesn't progress unless people do useful things with it.

Produced by Alexis Garcia and Justin Monticello. Camera by Garcia, Monticello, and Zach Weissmueller.

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Scientist claims he helped create world's first genetically-modified babies

In a video posted on YouTube, Chinese scientist He Jiankui announced to the world that he successfully used the gene-editing tool CRISPR-Cas9 to modify the DNA of two embryos before birth, essentially creating the world's first genetically modified humans. #CNN #News

Early results of human gene editing study encouraging

(5 Sep 2018) Partial results for gene editing study give promising signs that the treatment may be safe and have at least some of its hoped - for effect. But it is too soon to know whether it ultimately will prove successful (Sept 5)

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Jennifer Listgarten: CRISPR Gene Editing with Machine Learning

Computational Genomics Summer Institute 2017

Research Talk: CRISPR Gene Editing with Machine Learning
Jennifer Listgarten, Microsoft Research

Institute for Pure and Applied Mathematics, UCLA
July 10, 2017

For more information:

Human Nature | Official Trailer

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A breakthrough called CRISPR has given us unprecedented control over the basic building blocks of life. It opens the door to curing diseases, reshaping the biosphere, and designing our own children. Human Nature is a provocative exploration of CRISPR’s far-reaching implications, through the eyes of the scientists who discovered it, the families it’s affecting, and the bioengineers who are testing its limits. How will this new power change our relationship with nature? What will it mean for human evolution? To begin to answer these questions we must look back billions of years and peer into an uncertain future.


In Theaters March 13
Director: Adam Bolt

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Human Nature: Die CRISPR Revolution (OmU) - Offizieller Trailer

FSK=6

Human Nature: Die CRISPR Revolution ist ein Film über einen der größten wissenschaftlichen Durchbrüche des 21. Jahrhunderts – CRISPR. Extrahiert aus bakteriellen Immunsystemen ermöglicht die Genschere CRISPR-CAS9 in den Händen bahnbrechender Wissenschaftler heute eine nie dagewesene Kontrolle über die grundsätzlichsten Bausteine des Lebens. So öffnen sich Wege, um Krankheiten zu heilen, die gesamte Biosphäre umzugestalten und letztlich auch unsere eigenen Kinder zu designen. Die Setzung ethischer Grenzen hinkt diesem rasanten Fortschritt hinterher.
Human Nature vermittelt die Grundlagen der Genomforschung und ermöglicht so eine nachdenkliche Erkundung der weitreichenden Implikationen dieser revolutionären Technologie. In eingängigen Animationen zur Genetik und fesselnden Interviews mit renommierten Expert*innen betrachtet der Film die Standpunkte der Wissenschaftler*innen, die CRISPR entdeckten, der Familien, die von ihren Möglichkeiten betroffen sind, der Bioingenieur*innen, die mit ihr an die Grenzen des wissenschaftlich Möglichen gehen und auch der Firmen, die die Genschere ungeachtet der ungeklärten ethischen Fragen bereits gewinnbringend einsetzen.

Ab dem 06.03.2020 als VoD erhältlich!
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Humans, Gods and Technology | VPRO documentary | 2017

What will our world look like 25 years from now? Watch this lecture about the meaning of life shaped by technology in a near future.
Nobody knows how our world will look like in 25 years. Perhaps our work is taken over by autonomous robots and we become the slaves of the technology we have created ourselves. The big questions about the future of man and his relation to technology are presented to two important thinkers of the moment: Kevin Kelly and Yuval Noah Harari.
Kevin Kelly is a writer of influential works such as What Technology Wants and The Inevitable. Kelly sketches the inevitability of technology and even sees technology as an autonomous evolutionary system. Artificial intelligence becomes commonplace for everyone and will help us analyze difficult issues and challenge them to reflect on who we are. Kelly is convinced that we are already seen as Gods by technology and that robots will also believe in their own Gods.
Yuval Noah Harari is a writer of books about the history of Homo Sapiens and Homo Deus. Harari sketches the history of tomorrow and analyzes the way in which we create our own illusions; illusory institutions such as religion, states and money. We believe in gods because we want to be them ourselves. Harari sees a society with inequalities where some people can upgrade themselves to gods and others will remain vulnerable and mortal.

Originally broadcasted by VPRO in 2017.
© VPRO Backlight October 2017

On VPRO broadcast you will find nonfiction videos with English subtitles, French subtitles and Spanish subtitles, such as documentaries, short interviews and documentary series.
VPRO Documentary publishes one new subtitled documentary about current affairs, finance, sustainability, climate change or politics every week. We research subjects like politics, world economy, society and science with experts and try to grasp the essence of prominent trends and developments.

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Credits:
Director: Rob van Hattum
English, French and Spanish subtitles: Ericsson.
French and Spanish subtitles are co-funded by European Union.

What you need to know about CRISPR | Ellen Jorgensen

Should we bring back the wooly mammoth? Or edit a human embryo? Or wipe out an entire species that we consider harmful? The genome-editing technology CRISPR has made extraordinary questions like these legitimate — but how does it work? Scientist and community lab advocate Ellen Jorgensen is on a mission to explain the myths and realities of CRISPR, hype-free, to the non-scientists among us.

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Rewriting the Human Code: Dan Rather talks Gene Editing | SXSW LIVE STUDIO

Take a deep dive into SXSW with our Live Studio Interviews, where conversations go beyond the boundaries of sessions, showcases and screenings.

The ability to edit genetic code may be the breakthrough of the 21st century, but with this technology comes a host of ethical questions, each of which could have lasting impacts on humanity. Dan Rather stops by the studio with filmmaker Adam Bolt and News & Guts' Elliot Kirschner to discuss this with their new documentary film, Human Nature, which explores the potential consequences of this truly world-changing technology.

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Becoming immortal | VPRO documentary | 2018

Becoming immortal is now at hands reach, thanks to the latest technological innovations. Would you want to become immortal, even if that means preserving your severed head in a cryogenic tank? If aging is considered as a disease, then the cure is immortality. This is not a Black Mirror episode, this is VPRO Backlight: Becoming immortal.

Original title: De Onsterfelijken

Is eternal life reserved only for the rich or the lunatics of the earth? Silicon Valley is fascinated with the concept of overcoming death and rejuvenation. Billions are invested in becoming immortal. The idea is that when aging is considered as a disease, we can also develop a cure for dying and modify the natural lifecycle thanks to age reversing or anti aging therapy.

A tight community of scientists and entrepreneurs from Silicon Valley bear an enormous source of daring capital, like Aubrey de Grey says: ““If you’re not pissing everybody off in this life, then you’re probably not making much of a difference”.
This community is also firmly convinced that our DNA can be cracked in what would becalled: The code of mortality, allowing us all to become immortal.

And if becoming immortal does not happen within their own life span, then it will certainly happen in the following years. Therefore many a millionaire has his own personal cryogenic tank ready for cryopreservation so they can be brought back to life after death. Whether it will be in material form or in the form of a software program (digital immortality) or as nanobots remains to be seen.

Some can not wait that long and use themselves as guinea pigs. All of them hope to become immortal.
The science in the field of life extension is a booming business. The question remains whether everyone can benefit from this groundbreaking knowledge and become immortal.

With: Aubrey de Grey (Scientist), Liz Parrish (Bioviva), Darren Moore (Millionaire) and Kathleen Ann Goonan (Science-fiction writer), Linda Chamberlain (Alcor).
Originally broadcasted by VPRO in 2018.
© VPRO Backlight March 2018

On VPRO broadcast you will find nonfiction videos with English subtitles, French subtitles and Spanish subtitles, such as documentaries, short interviews and documentary series.
VPRO Documentary publishes one new subtitled documentary about current affairs, finance, sustainability, climate change or politics every week. We research subjects like politics, world economy, society and science with experts and try to grasp the essence of prominent trends and developments.

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Credits:
Directed by: Tomas Kaan
English, French and Spanish subtitles: Ericsson.
French and Spanish subtitles are co-funded by European Union.

Conversations in Science with Dan Rather & Jennifer Doudna: CRISPR

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In the last few years, the term CRISPR has exploded on the global scene, and with it UC Berkeley professor Jennifer Doudna, one of the pioneers in the field, has emerged into the spotlight. From magazine covers, to news broadcasts, to social media, CRISPR is the rare scientific breakthrough that has captivated the interest of the general public. But what is CRISPR really? What are its implications now and into the future? What profound ethical questions are raised by this ability to so precisely and easily edit the genome? In a candid and far-ranging conversation with Dan Rather, Doudna leads viewers through a nuanced and captivating view of this new technology. And along the way she shares her own improbable journey into science and her lessons for others - especially young women - who want to follow in her footsteps.

About the speakers:
Jennifer Doudna is Professor of the Departments of Chemistry and of Molecular and Cell Biology at University of California, Berkeley and an Investigator of the Howard Hughes Medical Institute. Early in her career, she studied the structure and mechanism of ribozymes (enzymatic RNA molecules) and RNA-protein complexes. Now her research focuses on understanding how RNA molecules control gene expression in bacteria and eukaryotic cells, through CRISPR-Cas9 and RNA-mediated mechanisms, respectively. For her outstanding scientific contributions, she was elected into the American Academy of Arts and Sciences in 2002 and the National Academy of Sciences in 2003, and was awarded the 2015 Breakthrough Prize in the Life Sciences. Learn more about Jennifer Doudna's research here:

Dan Rather has a resume that reads like a history book. He has interviewed every American president since Eisenhower and personally covered almost every important global dateline of the last 60 years, from the Civil Rights Movement to Vietnam, to Watergate to the terrorist attacks of 9/11. Rather helped pioneer the very idea that television could be a place for news, and he has kept that spirit of innovation alive by constantly pushing the boundaries of what video storytelling could accomplish. His independent production company News and Guts specializes in high-quality non-fiction content across a range of traditional and digital distribution channels. He has a special interest in telling the stories of science. Learn more about Dan Rather’s production company here:

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